ArticleBritish journal of cancer2013
Descriptive epidemiology of ependymal tumours in the United States.
Article in British journal of cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- The utilisation of fMRI for pre-operative mapping in the paediatric population with central nervous system tumours: a systematic review.Neuroradiology · 2025Pooled it
- Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort.Acta neuropathologica communications · 2022Pooled it
- Spinal ependymoma: a comprehensive review of molecular classification, management guidelines, and clinical outcomes with a focus on the pediatric population (Part III of ependymomas across compartments).Journal of neuro-oncology · 2026Review
- Long-term outcomes after adjuvant radiotherapy in adult spinal ependymomas: a multicenter study by the trod Neuro-Oncology research group (07 - 005).Journal of neuro-oncology · 2026Article
- Comprehensive characterization of spinal ependymomas in NF2-Schwannomatosis.Acta neuropathologica communications · 2026Article
- Giant intradural intramedullary spinal ependymoma: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Clinical Characteristics, Management, and Outcomes of Intramedullary Spinal Cord Ependymomas: A Systematic Review and Meta-Analysis.Spine surgery and related research · 2026Review
- Predictors of Long-Term Outcome and Recurrence of Intramedullary Spinal Ependymomas: A multicenter study.Neurosciences (Riyadh, Saudi Arabia) · 2026Article
- Adult ependymoma: results from the Dutch Brain Tumour Registry on primary treatment and survival.Journal of neuro-oncology · 2025Article
- Survival Patterns and Mortality Causes in Patients with Invasive Ependymoma: A Retrospective Cohort Analysis from 2000 to 2019.Medical sciences (Basel, Switzerland) · 2025Article
- Diagnostic Accuracy of MRI and CT Scan Features in Differentiation of Pediatric Ependymoma from Medulloblastoma.Iranian journal of child neurology · 2025Article
- Paediatric extra-axial myxopapillary ependymoma: what to expect? Case report and literature review.Frontiers in oncology · 2025Article
- Intracranial ependymoma: A retrospective analysis of clinical features, treatment modalities, and long-term outcome.Aging medicine (Milton (N.S.W)) · 2024Article
- Review
- Article
- Article
- Application of Drug Testing Platforms in Circulating Tumor Cells and Validation of a Patient-Derived Xenograft Mouse Model in Patient with Primary Intracranial Ependymomas with Extraneural Metastases.Diagnostics (Basel, Switzerland) · 2023Article
- Ependymomas in Children and Adults.Advances in experimental medicine and biology · 2023Article
- Citation analysis of the most influential ependymoma research articles illustrates improved knowledge of the molecular biology of ependymoma.Neurosurgical review · 2022Review
- Multisegment Intradural Extramedullary Ependymoma.Cureus · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundEpendymomas are rare primary gliomas that commonly affect both children and adults, but unique as survival is worse in children.
methodsData on brain and central nervous system primary malignant and non-malignant ependymal tumours from the Central Brain Tumor Registry of the United States analytic data set and primary malignant ependymal tumours from the SEER 13 registries research data file were used to evaluate incidence and survival, respectively.
resultsThe 2004-2009 average annual age-adjusted incidence rate of ependymal tumours was 0.41/100,000. Spinal cord/cauda equina was the primary site at diagnosis for 50-60% of ependymal tumours in adult age groups in contrast to about 20% in children and adolescents. Ependymoma was the most frequent histology in all age groups; however, anaplastic ependymoma comprised about 30% in cases 0-19 years of age compared with about 3-5% in adult age groups. Overall, relative survival was favourable with rates at ∼85% and 75% at 3 and 10 years post diagnosis, respectively. However, children and adolescents, the oldest adult age group, cases diagnosed with anaplastic ependymoma and/or tumour location in a brain site had lowest survival rates.
conclusionPaediatric cases had worse outcomes compared with adults for numerous reasons including having a higher percentage of anaplastic ependymomas and greater percentage of cases of intracranial disease.
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