Evidence map›Paper›PMID 23660685›Full record

ArticleLeukemia2013

Toward personalized therapy in AML: in vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML.

K M Bernot, R F Siebenaler, S P Whitman, N A Zorko, G G Marcucci, R Santhanam, E H Ahmed, M Ngangana, K K McConnell, J S Nemer and 13 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Coexistence ofTranslational cancer research · 2023
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. 11q23 abnormalities in adult Chinese patients with hematological malignancies.Medical oncology (Northwood, London, England) · 2014
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

K M Bernot1] The Comprehensive Cancer Center and The James Cancer Hospital and Solove Research Institute, Columbus, OH, USA [2] The Ohio State University, Columbus, OH, USA.
R F Siebenaler
S P Whitman
N A Zorko
G G Marcucci
R Santhanam
E H Ahmed
M Ngangana
K K McConnell
J S Nemer
D L Brook
S K Kulp
C S Chen
D Frankhouser
P Yan
R Bundschuh
X Zhang
A M Dorrance
K E Dickerson
D Jarjoura
W Blum
G Marcucci
M A Caligiuri

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
SPORE Leukemia Tissue BankP50CA140158 · NCI · OHIO STATE UNIVERSITY · PI BLOOMFIELD, CLARA D · 2009 to 2013
$11.2M
ONOCOLOGY TRAINING GRANTT32CA009338 · NCI · OHIO STATE UNIVERSITY · PI BYRD, JOHN C., POLLOCK, RAPHAEL E. · 1985 to 2018
$8.3M
PHARMACOLOGICAL MODULATION OF EPIGENETIC CHANTGES IN AMLR01CA102031 · NCI · OHIO STATE UNIVERSITY · PI GUZMAN, MONICA L, MARCUCCI, GUIDO · 2004 to 2017
$3.8M
Functional Characterization of MLL Gene FusionsR01CA089341 · NCI · OHIO STATE UNIVERSITY · PI CALIGIURI, MICHAEL A · 2002 to 2013
$2.8M
THE ROLE OF THE YEAST U2 ANALOGUE IN MRNA SPLICINGF32GM012453 · NIGMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI SHUSTER, ELIZABETH O · 1988 to 1989
–
NCI NIH HHS CA009338NCI NIH HHS CA089341NCI NIH HHS CA102031NCI NIH HHS CA140158NCI NIH HHS P30 CA016058NCI NIH HHS P50 CA140158NCI NIH HHS R01 CA089341NCI NIH HHS R01 CA102031NCI NIH HHS T32 CA009338NIGMS NIH HHS T32 GM12453
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epigenesis, GeneticPrecision MedicineAnimalsHistone-Lysine N-MethyltransferaseHumansLeukemia, Myeloid, AcuteMiceMice, KnockoutMyeloid-Lymphoid Leukemia ProteinHistone-Lysine N-MethyltransferaseKMT2A protein, humanMyeloid-Lymphoid Leukemia Protein

Identifiers

PMID23660685
PMCPMC3864138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.