Evidence map›Paper›PMID 23660413›Full record

ReviewCurrent opinion in cell biology2013

Envisioning migration: mathematics in both experimental analysis and modeling of cell behavior.

Elizabeth R Zhang, Lani F Wu, Steven J Altschuler

Open access · bronzeAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Quantifying Modes of 3D Cell Migration.Trends in cell biology · 2015
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Elizabeth R ZhangGreen Center for Systems Biology, Department of Pharmacology, Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. elizabeth.zhang@utsouthwestern.edu
Lani F Wu
Steven J Altschuler
Center for Systems Biology · USThe University of Texas Southwestern Medical Center · US

Funding

The design principles underlying cell polarity in yeastR01GM071794 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ALTSCHULER, STEVEN J · 2004 to 2012
$2.3M
Lung cancer heterogeneity and its impact on drug resistance.R01CA133253 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI ALTSCHULER, STEVEN J · 2010 to 2015
$2.3M
NCI NIH HHS R01 CA133253NCI NIH HHS R01CA133253NIGMS NIH HHS R01 GM071794
6 · The paper itself

Abstract

The complex nature of cell migration highlights the power and challenges of applying mathematics to biological studies. Mathematics may be used to create model equations that recapitulate migration, which can predict phenomena not easily uncovered by experiments or intuition alone. Alternatively, mathematics may be applied to interpreting complex data sets with better resolution--potentially empowering scientists to discern subtle patterns amid the noise and heterogeneity typical of migrating cells. Iteration between these two methods is necessary in order to reveal connections within the cell migration signaling network, as well as to understand the behavior that arises from those connections. Here, we review recent quantitative analysis and mathematical modeling approaches to the cell migration problem.

Indexed as

Cell MovementModels, BiologicalAnimalsHumansMathematicsSignal Transduction

Identifiers

PMID23660413
PMCPMC3758422
OpenAlexW2038957149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.