Evidence map›Paper›PMID 23660361›Full record

ReviewCurrent biology : CB2013

Integration of satiety signals by the central nervous system.

Adam P Chambers, Darleen A Sandoval, Randy J Seeley

Abstract readReview
In one paragraph

Review in Current biology : CB, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Cellular coding of ingestion in the caudal brainstem.bioRxiv : the preprint server for biology · 2026
    Article
  2. Review
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  7. Article
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  12. Review
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  16. Article
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  18. Adolescent eating behaviors in the UAE: Time to intervene.Journal of family medicine and primary care · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adam P ChambersMetabolic Diseases Institute, University of Cincinnati, 2170 E. Galbraith Road, Bldg E, 3rd Floor, ML 0503, Cincinnati, OH 45237, USA. adam.chambers@uc.edu
Darleen A Sandoval
Randy J Seeley

Funding

Dissecting mechanisms of GLP-1 based therapies for Type II DiabetesR01DK093848 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEELEY, RANDY J · 2012 to 2015
$1.5M
CIHRNIDDK NIH HHS 1R01DK093848NIDDK NIH HHS R01 DK093848
6 · The paper itself

Abstract

Individual meals are products of a complex interaction of signals related to both short-term and long-term availability of energy stores. In addition to maintaining the metabolic demands of the individual in the short term, levels of energy intake must also maintain and defend body weight over longer periods. To accomplish this, satiety pathways are regulated by a sophisticated network of endocrine and neuroendocrine pathways. Higher brain centers modulate meal size through descending inputs to caudal brainstem regions responsible for the motor pattern generators associated with ingestion. Gastric and intestinal signals interact with central nervous system pathways to terminate food intake. These inputs can be modified as a function of internal metabolic signals, external environmental influences, and learning to regulate meal size.

Indexed as

EatingEnergy IntakeSatiationSignal TransductionAnimalsCentral Nervous SystemHormonesHumansMiceNeurosecretory SystemsRatsHormones

Identifiers

PMID23660361
PMCPMC3688053

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.