Evidence map›Paper›PMID 23660352›Full record

ArticleCurrent biology : CB2013

Microbial evolution: regulatory design prevents cancer-like overgrowths.

Steven A Frank

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Variability in fitness effects can preclude selection of the fittest.Annual review of ecology, evolution, and systematics · 2017
    Article
  3. Article
  4. Article
  5. First principles of Hamiltonian medicine.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Steven A FrankDepartment of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697-2525, USA. safrank@uci.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutant lineages may cause cancer-like overgrowths in microbial populations. Theory predicts that microbial regulatory controls may be designed to limit the origin and competitive potential of rogue lineages. A new study shows how a Salmonella species protects itself against overgrowths.

Indexed as

Biological EvolutionPhenotypeAnimalsSalmonella typhimurium

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.