ArticleThe world journal of men's health2013
Current issues in varicocele management: a review.
Article in The world journal of men's health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- The Influence of Number of Ligated Veins in Varicocele Patients Undergoing Microsurgical Varicocelectomy in Postoperative Pain and Sperm Parameters Outcome.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2023Pooled it
- Surgical or radiological treatment for varicoceles in subfertile men.The Cochrane database of systematic reviews · 2021Pooled it
- Comparison of DNA fragmentation index and fertility rate after unilateral and bilateral microsurgical varicocelectomy.European journal of translational myology · 2025Article
- Risk factors associated with varicocele: a narrative review.Translational andrology and urology · 2025Review
- N6-methyladenosine modification of PLOD2 causes spermatocyte damage in rats with varicocele.Cellular & molecular biology letters · 2023Article
- Association between body mass index and varicocele among 211 989 Chinese reproductive-age males.International journal of urology : official journal of the Japanese Urological Association · 2022Article
- Role of Oxidative Stress in Varicocele.Frontiers in genetics · 2022Review
- Down regulating PHGDH affects the lactate production of sertoli cells in varicocele.Reproductive biology and endocrinology : RB&E · 2020Article
- Effect of microsurgical varicocelectomy on semen parameters, serum, and intratesticular testosterone levels.BJUI compass · 2020Article
- Article
- Current Issues in Adolescent Varicocele: Pediatric Urological Perspectives.The world journal of men's health · 2018Review
- Genetics and epigenetics of varicocele pathophysiology: an overview.Journal of assisted reproduction and genetics · 2017Review
- Varicocelectomy: Modified loupe-assisted versus microscopic technique - A prospective comparative study.Arab journal of urology · 2017Article
- Efficacy and safety of 0.75% ropivacaine instillation into subinguinal wound in patients after bilateral microsurgical varicocelectomy: a bi-center, randomized, double-blind, placebo-controlled trial.Journal of pain research · 2017Article
- Treatment effect of TUSPLV on recurrent varicocele.Experimental and therapeutic medicine · 2017Article
- Effects of varicocelectomy on serum testosterone.Translational andrology and urology · 2016Review
- Leg ischemia post-varicocelectomy.International medical case reports journal · 2016Article
- Anatomical factors affecting the time required for microsurgical subinguinal varicocelectomy.SpringerPlus · 2016Article
- Effects ofEvidence-based complementary and alternative medicine : eCAM · 2016Article
- Treatment of male varicoceles by transcatheter polidocanol foam sclerotherapy: evaluation of clinical success, complications, and patients' satisfaction with regard to alternative techniques.European radiology · 2015Observational
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most common cause of male infertility is varicocele, and varicocele is the most common correctable cause of male factor infertility. In this article we reviewed the concept of varicocele in terms of its diagnosis, method of treatment, indications for treatment, treatment outcomes, and prognostic factors. Physical examination is an essential diagnostic tool in the evaluation of a patient with a varicocele. However, as it depends on subjective findings, standardization of the physical examination method is needed. Various methods for treatment of varicocele exist, including open surgical, laparoscopic, microscopic surgical, and radiologic treatment such as embolization. Among these treatment approaches, microscopic inguinal or subinguinal varicocelectomy has superior outcomes, with a low complication rate. The influence of the treatment of varicocele on fertility is still a controversial issue and a difficult question to address, because there are limitations to performing a randomized control study, and previous studies had a heterogeneity of subjects and high dropout rate. However, there is robust evidence that varicocelectomy improves semen parameters as a surrogate marker of the potential for fertility. To date, general indications for treatment of varicocele are limited in patients with proven infertility, clinical palpable varicocele, and abnormal semen characteristics. Recently, it was shown that some symptoms other than infertility could be an indication for varicocelectomy because these symptoms are frequently related to deterioration of semen parameters. Varicocele in the adolescent presents a more difficult decision regarding whether to treat. A testicular size discrepancy of more than 20% is helpful for treatment decisions. Various prognostic factors were noted in several studies without, however, a consistent consensus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.