ArticlePloS one2013
The roles of noradrenergic and glucocorticoid activation in the development of intrusive memories.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- A systematic review and meta-analysis of experimental methods for modulating intrusive memories following lab-analogue trauma exposure in non-clinical populations.Nature human behaviour · 2024Pooled it
- Intrusive memories of trauma: A target for research bridging cognitive science and its clinical application.Clinical psychology review · 2019Pooled it
- Can't get it out of my mind: A systematic review of predictors of intrusive memories of distressing events.Psychological bulletin · 2018Pooled it
- The effects of acute stress on episodic memory: A meta-analysis and integrative review.Psychological bulletin · 2017Pooled it
- Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study.Addiction biology · 2023Trial
- Oxytocin vs. placebo effects on intrusive memory consolidation using a trauma film paradigm: a randomized, controlled experimental study in healthy women.Translational psychiatry · 2023Trial
- Real-World Intake of Dietary Sugars Is Associated with Reduced Cortisol Reactivity Following an Acute Physiological Stressor.Nutrients · 2023Article
- Post-Encoding Stress Does Not Enhance Memory Consolidation: The Role of Cortisol and Testosterone Reactivity.Brain sciences · 2020Article
- The effects of post-encoding stress and glucocorticoids on episodic memory in humans and rodents.Brain and cognition · 2019Review
- Imagery retrieval may explain why recall of negative scenes contains more accurate detail.Memory & cognition · 2019Article
- The Current Evidence for Acute Stress Disorder.Current psychiatry reports · 2018Review
- A prospective examination of risk factors in the development of intrusions following a trauma analog.Behaviour research and therapy · 2017Article
- Intrusive memories to traumatic footage: the neural basis of their encoding and involuntary recall.Psychological medicine · 2016Article
- Activating Attachments Reduces Memories of Traumatic Images.PloS one · 2016Article
- Association of BDNF Val66Met polymorphism with HPA and SAM axis reactivity to psychological and physical stress.Neuropsychiatric disease and treatment · 2014Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intrusive memories are a common feature of many psychological disorders. Recent evidence has potentially extended cognitive models of intrusions by identifying the role of biological markers of arousal at the time of consolidation in subsequent memory for emotional events. This study investigated the role of arousal during consolidation in the development of intrusive memories. Seventy-eight university students (37 men and 41 women) viewed 20 negative and 20 neutral images. Half the participants then underwent a cold pressor test (High Stress), immersing their hand in ice water, while the remaining participants immersed their hand in warm water (Low Stress). Samples of salivary alpha-amylase (sAA) and cortisol were collected from participants at baseline and following the stressor challenge. Participants completed a delayed free recall test and intrusion questionnaires two days later. Participants in the High Stress condition reported more intrusions of negative images than participants in the Low Stress condition. An interaction variable in a linear regression of increased noradrenergic and cortisol values predicted intrusive memories of emotional stimuli for men but not women. These findings are consistent with recent evidence of the combined effects of noradrenaline and corticoid responses to stress on emotional memories, and also with increasing evidence of gender differences in how stress hormones influence formation of emotional memories. These findings point to possible mechanisms by which development of intrusions may be prevented after consolidation of traumatic experiences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.