ArticlePloS one2013
A cryptic cytoplasmic male sterility unveils a possible gynodioecious past for Arabidopsis thaliana.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 39 citations in OpenAlex.
- Artificial Mutations in the Nuclear Gene Encoding Mitochondrial RNA Polymerase Restore Pollen Fertility in Cytoplasmic Male Sterile Tomato.Plant biotechnology journal · 2026Article
- The molecular evolutionary basis of species formation revisited.Trends in genetics : TIG · 2025Review
- The evolutionary dynamics of organellar pan-genomes in Arabidopsis thaliana.Genome biology · 2025Article
- Fluctuating reproductive isolation and stable ancestry structure in a fine-scaled mosaic of hybridizing Mimulus monkeyflowers.PLoS genetics · 2025Article
- Long-read sequencing characterizes mitochondrial and plastid genome variants in Arabidopsis msh1 mutants.The Plant journal : for cell and molecular biology · 2022Article
- APOK3, a pollen killer antidote in Arabidopsis thaliana.Genetics · 2022Article
- Cytonuclear Genetic Incompatibilities in Plant Speciation.Plants (Basel, Switzerland) · 2020Review
- Reciprocal cybrids reveal how organellar genomes affect plant phenotypes.Nature plants · 2020Article
- No evidence for strong cytonuclear conflict over sex allocation in a simultaneously hermaphroditic flatworm.BMC evolutionary biology · 2017Article
- Genomic Conflicts that Cause Pollen Mortality and Raise Reproductive Barriers in Arabidopsis thaliana.Genetics · 2016Article
- Cytonuclear interactions affect adaptive traits of the annual plant Arabidopsis thaliana in the field.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- The Propensity of Pentatricopeptide Repeat Genes to Evolve into Restorers of Cytoplasmic Male Sterility.Frontiers in plant science · 2016Review
- MutS HOMOLOG1 silencing mediates ORF220 substoichiometric shifting and causes male sterility in Brassica juncea.Journal of experimental botany · 2016Article
- Cytoplasmic male sterility in Brassicaceae crops.Breeding science · 2014Review
- RNA processing factor 7 and polynucleotide phosphorylase are necessary for processing and stability of nad2 mRNA in Arabidopsis mitochondria.RNA biology · 2014Article
- P-class pentatricopeptide repeat proteins are required for efficient 5' end formation of plant mitochondrial transcripts.RNA biology · 2013Review
- Review
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9 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Gynodioecy, the coexistence of hermaphrodites and females (i.e. male-sterile plants) in natural plant populations, most often results from polymorphism at genetic loci involved in a particular interaction between the nuclear and cytoplasmic genetic compartments (cytonuclear epistasis): cytoplasmic male sterility (CMS). Although CMS clearly contributes to the coevolution of involved nuclear loci and cytoplasmic genomes in gynodioecious species, the occurrence of CMS genetic factors in the absence of sexual polymorphism (cryptic CMS) is not easily detected and rarely taken in consideration. We found cryptic CMS in the model plant Arabidopsis thaliana after crossing distantly related accessions, Sha and Mr-0. Male sterility resulted from an interaction between the Sha cytoplasm and two Mr-0 genomic regions located on chromosome 1 and chromosome 3. Additional accessions with either nuclear sterility maintainers or sterilizing cytoplasms were identified from crosses with either Sha or Mr-0. By comparing two very closely related cytoplasms with different male-sterility inducing abilities, we identified a novel mitochondrial ORF, named orf117Sha, that is most likely the sterilizing factor of the Sha cytoplasm. The presence of orf117Sha was investigated in worldwide natural accessions. It was found mainly associated with a single chlorotype in accessions belonging to a clade predominantly originating from Central Asia. More than one-third of accessions from this clade carried orf117Sha, indicating that the sterilizing-inducing cytoplasm had spread in this lineage. We also report the coexistence of the sterilizing cytoplasm with a non-sterilizing cytoplasm at a small, local scale in a natural population; in addition a correlation between cytotype and nuclear haplotype was detected in this population. Our results suggest that this CMS system induced sexual polymorphism in A. thaliana populations, at the time when the species was mainly outcrossing.
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