ArticleJournal of virology2013
Comparison of the levels of infectious virus in respirable aerosols exhaled by ferrets infected with influenza viruses exhibiting diverse transmissibility phenotypes.
Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 54 citations in OpenAlex.
- Heterogeneous shedding of influenza by human subjects and its implications for epidemiology and control.Scientific reports · 2016Trial
- Risk assessment of avian influenza A(H5N5) virus from the first human case using the ferret model.Journal of virology · 2026Article
- Advancing A(H5N1) influenza risk assessment in ferrets through comparative evaluation of airborne virus shedding patterns.Nature communications · 2026Article
- Size distribution and viral RNA load of influenza virus-laden airborne particles emitted from pigs over the course of an H1N1 infection.Scientific reports · 2025Article
- Propylene glycol inactivates respiratory viruses and prevents airborne transmission.EMBO molecular medicine · 2023Article
- Kinetics and magnitude of viral RNA shedding as indicators for Influenza A virus transmissibility in ferrets.Communications biology · 2023Article
- Article
- Inherent Heterogeneity of Influenza A Virus Stability following Aerosolization.Applied and environmental microbiology · 2022Article
- Maintaining differential pressure gradients does not increase safety inside modern BSL-4 laboratories.Frontiers in bioengineering and biotechnology · 2022Article
- SARS-CoV-2 indoor air transmission is a threat that can be addressed with science.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Non-respiratory particles emitted by guinea pigs in airborne disease transmission experiments.Scientific reports · 2021Article
- Influenza A virus is transmissible via aerosolized fomites.Nature communications · 2020Article
- Ferreting Out Influenza Virus Pathogenicity and Transmissibility: Past and Future Risk Assessments in the Ferret Model.Cold Spring Harbor perspectives in medicine · 2020Review
- Estimated Inactivation of Coronaviruses by Solar Radiation With Special Reference to COVID-19.Photochemistry and photobiology · 2020Article
- Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity.PLoS pathogens · 2020Article
- Swine-Origin H1 Influenza Viruses Isolated from Humans Exhibit Sustained Infectivity in an Aerosol State.Applied and environmental microbiology · 2019Article
- Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments.Emerging infectious diseases · 2018Article
- Recently Identified Mutations in the Ebola Virus-Makona Genome Do Not Alter Pathogenicity in Animal Models.Cell reports · 2018Article
- Experimental infection of Cynomolgus Macaques with highly pathogenic H5N1 influenza virus through the aerosol route.Scientific reports · 2018Article
- Defining the sizes of airborne particles that mediate influenza transmission in ferrets.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Influenza viruses pose a major public health burden to communities around the world by causing respiratory infections that can be highly contagious and spread rapidly through the population. Despite extensive research on influenza viruses, the modes of transmission occurring most often among humans are not entirely clear. Contributing to this knowledge gap is the lack of an understanding of the levels of infectious virus present in respirable aerosols exhaled from infected hosts. Here, we used the ferret model to evaluate aerosol shedding patterns and measure the amount of infectious virus present in exhaled respirable aerosols. By comparing these parameters among a panel of human and avian influenza viruses exhibiting diverse respiratory droplet transmission efficiencies, we are able to report that ferrets infected by highly transmissible influenza viruses exhale a greater number of aerosol particles and more infectious virus within respirable aerosols than ferrets infected by influenza viruses that do not readily transmit. Our findings improve our understanding of the ferret transmission model and provide support for the potential for influenza virus aerosol transmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.