Evidence map›Paper›PMID 23658094›Full record

ReviewThe International journal of eating disorders2013

Biological therapies for eating disorders.

James E Mitchell, James Roerig, Kristine Steffen

Open access · bronzeAbstract readReview
In one paragraph

Review in The International journal of eating disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
10.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

James E MitchellNeuropsychiatric Research Institute, Fargo, North Dakota 58102, USA. Mitchell@medicine. nodak.edu
James Roerig
Kristine Steffen
University of North Dakota · USNeuropsychiatric Research Institute · US

Funding

Longitudinal Assessment of Bariatric Surgery (LABS)U01DK066471 · NIDDK · SANFORD RESEARCH NORTH · PI MITCHELL, JAMES EDWARD · 2003 to 2015
$3.7M
Psychosocial Issues and Bariatric SurgeryR01DK084979 · NIDDK · SANFORD RESEARCH NORTH · PI MITCHELL, JAMES EDWARD · 2010 to 2017
$2.8M
DELIVERING CBT TO PATIENTS WITH BN IN RURAL SETTINGSR01MH058820 · NIMH · SANFORD RESEARCH NORTH · PI MITCHELL, JAMES EDWARD · 1999 to 2008
$1.8M
A Pharmacokinetic Comparison of Sertraline Before and After Bariatric SurgeryK23DK085066 · NIDDK · SANFORD RESEARCH NORTH · PI STEFFEN, KRISTINE JAYNE · 2010 to 2014
$794k
NIDDK NIH HHS K23 DK085066NIDDK NIH HHS R01 DK084979NIDDK NIH HHS R01 DK84979NIDDK NIH HHS U01 DK066471NIDDK NIH HHS UO1 DK066471NIMH NIH HHS R01 MH058820
6 · The paper itself

Abstract

objectiveTo provide a comprehensive review of pharmacotherapy and other biological treatments for eating disorders.

methodLiterature on this topic was systematically reviewed.

resultsThe bulimia nervosa (BN) literature underscores the utility of antidepressants, particularly SSRIs, in improving the symptoms of the disorder. The literature on binge eating disorder supports efficacy on reduction in binge eating frequency for a variety of compounds. However, such compounds have only modest effects on weight. Certain antiepileptic agents such as topiramate, if tolerated, are probably more useful in terms of weight loss. The number of controlled trials in patients with anorexia nervosa (AN) in particular has been quite small, and recent meta-analyses show disappointing results using atypical antipsychotics in AN. DISCUSSION: The pharmacological treatment of eating disorders remains an underdeveloped field although drug therapy clearly plays a role in the treatment of those with BN and binge eating disorder. Other biological therapies have not been adequately studied.

Indexed as

Antidepressive AgentsAntipsychotic AgentsCognitive Behavioral TherapyFeeding and Eating DisordersHumansAntidepressive AgentsAntipsychotic Agents

Identifiers

PMID23658094
PMCPMC4372845
OpenAlexW2157829642

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.