← Metformin × hypoglycaemia

SynthesisEndocrine2013

The effects of sulfonylureas plus metformin on lipids, blood pressure, and adverse events in type 2 diabetes: a meta-analysis of randomized controlled trials.

Fan Zhang et al.PubMed ↗Publisher ↗

What the trial testedas reported · 2013

Not counted

Probably raised hypoglycaemia

6.8×3.8× to 12×

Bigger than almost all on the map

As reported

RR 6.79, 95% CI 3.79–12.2

Not counted

Probably raised hypoglycaemia

+27%+3% to +57%

Bigger than 5 in 10 on the map

As reported

RR 1.27, 95% CI 1.03–1.57

Not counted

Probably lowered hypoglycaemia

−25%−33% to −16%

Bigger than 6 in 10 on the map

As reported

RR 0.75, 95% CI 0.67–0.84

Three numbers in the abstract

the abstract, start to end

… metformin than metformin alone (RR = 6.79, 95 % CI 3.79-12.17; RR = 1.27, 95 % CI 1.03-1.57; respectively), but less in digestive symptoms (RR = 0.75, 95 % CI 0.67-0.84).

← favours treatmentfavours comparator →
could be chance
Hypoglycaemia
RR 6.793.79–12.2
Hypoglycaemia
RR 1.271.03–1.57
Hypoglycaemia
RR 0.750.67–0.84
MetforminSulfonylureas & glinidesHypoglycaemia
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Full record →Abstract, authors, funding and every citing paper · PMID 23657947