ArticleMolecular biology reports2013
Nanofiber-based polyethersulfone scaffold and efficient differentiation of human induced pluripotent stem cells into osteoblastic lineage.
Article in Molecular biology reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Induced pluripotent stem cells as a new getaway for bone tissue engineering: A systematic review.Cell proliferation · 2017Pooled it
- The generation of islet-like insulin-producing cells from Wharton's jelly-derived mesenchymal stem cells on the PES/fish gelatin scaffold.Regenerative therapy · 2024Article
- Open fractures: Current treatment perspective.OTA international : the open access journal of orthopaedic trauma · 2023Article
- Novel cell sources for bone regeneration.MedComm · 2021Review
- Induced Pluripotent Stem Cells in Dental and Nondental Tissue Regeneration: A Review of an Unexploited Potential.Stem cells international · 2020Review
- Induced Osteogenesis in Plants Decellularized Scaffolds.Scientific reports · 2019Article
- Bone physiology as inspiration for tissue regenerative therapies.Biomaterials · 2018Review
- Treatment of critical-sized bone defects: clinical and tissue engineering perspectives.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2018Review
- Low Osteogenic Yield in Human Pluripotent Stem Cells Associates with Differential Neural Crest Promoter Methylation.Stem cells (Dayton, Ohio) · 2018Article
- Construction of human induced pluripotent stem cell-derived oriented bone matrix microstructure by using in vitro engineered anisotropic culture model.Journal of biomedical materials research. Part A · 2018Article
- Artificial Bone via Bone Tissue Engineering: Current Scenario and Challenges.Tissue engineering and regenerative medicine · 2017Review
- Enhanced osteoconductivity of polyethersulphone nanofibres loaded with bioactive glass nanoparticles in in vitro and in vivo models.Cell proliferation · 2015Article
- Tissue Engineering and Regenerative Medicine in Iran: Current State of Research and Future Outlook.Molecular biotechnology · 2015Review
- Bone tissue engineering via human induced pluripotent, umbilical cord and bone marrow mesenchymal stem cells in rat cranium.Acta biomaterialia · 2015Article
- Comparison of osteogenic differentiation potential of human adult stem cells loaded on bioceramic-coated electrospun poly (L-lactide) nanofibres.Cell proliferation · 2015Article
- Article
- Mineralized gelatin methacrylate-based matrices induce osteogenic differentiation of human induced pluripotent stem cells.Acta biomaterialia · 2014Article
- Comparison of random and aligned PCL nanofibrous electrospun scaffolds on cardiomyocyte differentiation of human adipose-derived stem cells.Iranian journal of basic medical sciences · 2014Article
- Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC) Derived Hepatocyte-Like Cells on hMSCs Feeder.International journal of hematology-oncology and stem cell research · 2014Article
- Comparison of different protocols for neural differentiation of human induced pluripotent stem cells.Molecular biology reports · 2014Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human induced pluripotent stem cells (iPSCs) have been shown to have promising potential for regenerative medicine and tissue engineering applications. In the present study, osteogenic differentiation of human iPSCs was evaluated on polyethersulfone (PES) nanofibrous scaffold. According to the results, higher significant expressions of common osteogenic-related genes such as runx2, collagen type I, osteocalcin and osteonectin was observed in PES seeded human iPSCs compared with control. Alizarin red staining and alkaline phosphatase activity of differentiated iPSCs demonstrated significant osteoblastic differentiation potential of these cells. In this study biocompatibility of PES nanofibrous scaffold confirmed by flattened and spreading morphology of iPSCs under osteoblastic differentiation inductive culture. Taking together, nanofiber-based PES scaffold seeded iPSCs showed the highest capacity for differentiation into osteoblasts-like cells. These cells and PES scaffold were demonstrated to have great efficiency for treatment of bone damages and lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.