Trial reportInternational journal of colorectal disease2013
Normal values and pressure morphology for three-dimensional high-resolution anorectal manometry of asymptomatic adults: a study in 110 subjects.
Trial report in International journal of colorectal disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 93 citations in OpenAlex.
- Trial
- Total anorectal reconstruction with gracilis muscle flap-assisted coloplasty following abdominoperineal resection: a case report.International journal of colorectal disease · 2026Article
- Urinary Dysfunction Is Common in Patients with Fecal Urgency and May Relate to Altered Rectal Biomechanics.Digestive diseases and sciences · 2025Article
- Age-stratified diagnostic value of high-resolution anorectal manometry in women with severe rectocele: interactions between anal relaxation rate and maximum anal resting pressure.International journal of colorectal disease · 2025Article
- Mucosal advancement flap versus ligation of the inter-sphincteric fistula tract for management of trans-sphincteric perianal fistulas in the elderly: a retrospective study.International journal of colorectal disease · 2025Observational
- Article
- High-Resolution Anorectal Manometry and Balloon Expulsion Test Outcomes in Functional Constipation: A Comparative Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- High-resolution anorectal manometry for diagnosing obstructed defecation syndrome associated with moderate rectocele compared to healthy individuals.BMC gastroenterology · 2024Article
- Optimizing the Utility of Anorectal Manometry for Diagnosis and Therapy: A Roundtable Review and Recommendations.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Review
- Study on 3D High-Resolution Anorectal Manometry Interrater Agreement in the Evaluation of Dyssynergic Defecation Disorders.Diagnostics (Basel, Switzerland) · 2023Article
- Evaluation of Anal Sphincter with High Resolution Anorectal Manometry and 3D Reconstruction in Patients with Anorectal Malformation.Children (Basel, Switzerland) · 2023Article
- Age- and Gender-Based Differences in Anorectal Function, Gastrointestinal Symptoms, and Constipation-Specific Quality of Life in Patients with Chronic Constipation.Digestive diseases and sciences · 2023Article
- To what extent are anorectal function tests comparable? A study comparing digital rectal examination, anal electromyography, 3-dimensional high-resolution anal manometry, and transperineal ultrasound.International journal of colorectal disease · 2023Article
- Effects of Aging and Gender on the Anorectal Function of Healthy Subjects Assessed with Conventional Anorectal Manometry.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022Article
- Anorectal volume-pressure relations, contraction work, and flow during defecation.Biomechanics and modeling in mechanobiology · 2022Article
- Review of the indications, methods, and clinical utility of anorectal manometry and the rectal balloon expulsion test.Neurogastroenterology and motility · 2022Review
- Feasibility study of defecation studied with a wireless Fecobionics probe in normal subjects.Physiological reports · 2022Article
- Anorectal dysfunction in patients with mid-low rectal cancer after surgery: A pilot study with three-dimensional high-resolution manometry.World journal of clinical cases · 2022Article
- Redundancy in the International Anorectal Physiology Working Group Manometry Protocol: A Diagnostic Accuracy Study in Fecal Incontinence.Digestive diseases and sciences · 2022Article
- Normal values for high-resolution anorectal manometry in healthy young adults: evidence from Vietnam.BMC gastroenterology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of this study is to evaluate normal values and pressure morphology of three-dimensional high-resolution anorectal manometry (3D-HRM) in asymptomatic volunteers and to determine the relationship between objective measurable values, gender, and age. PATIENTS AND
methodsAnorectal pressures and rectal sensation were evaluated in 110 asymptomatic volunteers (46 females and 64 males) ranging in age from 18 to 80 years (median age, 52 years) in left lateral position by three-dimensional high-resolution manometry.
resultsMaximum squeeze pressure, residual anal pressure, and intrarectal pressure were significantly higher in males compared to females (p < 0.05 each). Duration of sustained squeeze was significantly lower in males compared to females (p < 0.05). Maximum resting pressure, mean resting pressure, and maximum squeeze pressure were inversely correlated (r = -0.310, p < 0.01, r = -0.276, p < 0.01, and r = -0.198, p < 0.05) with age. The value of rectoanal pressure differential was -13.1 ± 5.8 mmHg which was negative during defecation. Overall variation coefficient in anorectal pressures ranged between 0.21 and 0.34.
conclusionThis study establishes normal values for anorectal pressure by 3D-HRM in asymptomatic volunteers. There are significant gender differences concerning squeeze patterns. Increasing age is associated with lower maximum resting pressure, mean resting pressure, and maximum squeeze pressure. Normal characteristic pressure morphology of anorectum can be obtained at rest, during squeeze, and bear down as in defecation by 3D-HRM.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.