Evidence map›Paper›PMID 23656830›Full record

SynthesisHarvard review of psychiatry

Depressive symptoms after CABG surgery: a meta-analysis.

Simha Ravven, Caroline Bader, Armin Azar, James L Rudolph

Registry-linked trialAbstract readMeta-Analysis
In one paragraph

Synthesis in Harvard review of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06706323 (Predictive Modelling of Clinically Significant Depressive Symptoms After Coronary Artery Bypass Graft Surgery), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06706323 recruitingnot on this map

Predictive Modelling of Clinically Significant Depressive Symptoms After Coronary Artery Bypass Graft Surgery

TypeobservationalSponsorRoland von KänelRan2024 to 2027Enrolled300ConditionsCardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Depression
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Relationship between depression and health-related quality of life in patients undergoing coronary artery bypass grafting: a MOTIV-CABG substudy.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016
    Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simha RavvenHarvard Medical School, Boston, MA, USA.
Caroline Bader
Armin Azar
James L Rudolph

Funding

Greater Boston Medical Student Training in Aging ResearchT35AG038027 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI DRIVER, JANE A, MCLAUGHLIN-GAVIN, CARA · 2010 to 2024
$991k
NIA NIH HHS AG038027-01NIA NIH HHS T35 AG038027
6 · The paper itself

Abstract

LEARNING

objectivesAfter participating in this educational activity, the reader should be better able to measure the risk of depression before and after coronary artery bypass graft (CABG) surgery; examine the course of depression after CABG; and apply the results of the study to the treatment of patients.

objectiveDepression is highly comorbid with coronary artery disease. Clinicians face the question of whether patients' depressive symptoms will improve after coronary artery bypass graft surgery (CABG). The objective of this meta-analysis is to determine the course of depressive symptoms after CABG.

methodsEMBASE, PubMed, and PsycINFO were searched for studies assessing depression before and after CABG. Meta-analyses were performed for depression at early (1-2 weeks), recovery (>2 weeks to 2 months), mid (>2 months to 6 months), and late (>6 months) postoperative time points. Heterogeneity and publication bias were analyzed.

resultsThirty-nine studies were included in the meta-analysis. Twelve reported dichotomous outcomes; 18 reported continuous outcomes; and 9 reported both. Risk of depression was increased early (relative risk [RR] = 1.27; 95% confidence interval [CI], 1.01-1.61). There was a significantly decreased risk of depression at recovery (RR = 0.78; 95% CI, 0.67-0.90), mid (RR = 0.64; 95% CI, 0.58-0.70), and late (RR = 0.68; 95% CI, 0.58-0.79) time points without heterogeneity. All studies reporting continuous depression scales had significant heterogeneity.

conclusionsThe risk of depression decreased post-CABG when depression was measured dichotomously. While depression improves overall and remits for some patients after CABG, the majority of patients will not experience remission of depression. Preoperative and postoperative depression monitoring is important.

Indexed as

Treatment OutcomeCoronary Artery BypassCoronary Artery DiseaseDepressionHumans

Identifiers

PMID23656830
PMCPMC3652273

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.