ArticleAstrobiology2013
Observations of interstellar formamide: availability of a prebiotic precursor in the galactic habitable zone.
Article in Astrobiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 93 citations in OpenAlex.
- Prospects of formamide as nitrogen source in biotechnological production processes.Applied microbiology and biotechnology · 2024Review
- Light-Assisted Formation of Nucleosides and Nucleotides from Formamide in the Presence of Cerium Phosphate.Life (Basel, Switzerland) · 2024Article
- Prebiotic Syntheses of Organophosphorus Compounds from Reduced Source of Phosphorus in Non-Aqueous Solvents.Life (Basel, Switzerland) · 2023Article
- Peptide Bonds in the Interstellar Medium: Facile Catalytic Formation from Nitriles on Water-Ice Grains.The journal of physical chemistry. A · 2023Article
- Results of an Eight-Year Extraction of Phosphorus Minerals within the Seymchan Meteorite.Life (Basel, Switzerland) · 2022Article
- On the Capability of Oxidovanadium(IV) Derivatives to Act as All-Around Catalytic Promoters Since the Prebiotic World.Molecules (Basel, Switzerland) · 2020Review
- Astrochemistry and Astrobiology: Materials Sciencein Wonderland?International journal of molecular sciences · 2019Review
- A Universal Geochemical Scenario for Formamide Condensation and Prebiotic Chemistry.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Review
- Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA.Life (Basel, Switzerland) · 2018Review
- The Prevailing Catalytic Role of Meteorites in Formamide Prebiotic Processes.Life (Basel, Switzerland) · 2018Review
- Estimating the capacity for production of formamide by radioactive minerals on the prebiotic Earth.Scientific reports · 2018Article
- Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context.Scientific reports · 2017Article
- Silicate-Promoted Phosphorylation of Glycerol in Non-Aqueous Solvents: A Prebiotically Plausible Route to Organophosphates.Life (Basel, Switzerland) · 2017Article
- First Evidence on the Role of Heavy Ion Irradiation of Meteorites and Formamide in the Origin of Biomolecules.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2016Article
- A Global Scale Scenario for Prebiotic Chemistry: Silica-Based Self-Assembled Mineral Structures and Formamide.Biochemistry · 2016Article
- Prebiotic chemical evolution in the astrophysical context.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2015Article
- Meteorite-catalyzed syntheses of nucleosides and of other prebiotic compounds from formamide under proton irradiation.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- From formamide to RNA, the path is tenuous but continuous.Life (Basel, Switzerland) · 2015Article
- Impact synthesis of the RNA bases.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We conducted a study on interstellar formamide, NH2CHO, toward star-forming regions of dense molecular clouds, using the telescopes of the Arizona Radio Observatory (ARO). The Kitt Peak 12 m antenna and the Submillimeter Telescope (SMT) were used to measure multiple rotational transitions of this molecule between 100 and 250 GHz. Four new sources of formamide were found [W51M, M17 SW, G34.3, and DR21(OH)], and complementary data were obtained toward Orion-KL, W3(OH), and NGC 7538. From these observations, column densities for formamide were determined to be in the range of 1.1×10(12) to 9.1×10(13) cm(-2), with rotational temperatures of 70-177 K. The molecule is thus present in warm gas, with abundances relative to H2 of 1×10(-11) to 1×10(-10). It appears to be a common constituent of star-forming regions that foster planetary systems within the galactic habitable zone, with abundances comparable to that found in comet Hale-Bopp. Formamide's presence in comets and molecular clouds suggests that the compound could have been brought to Earth by exogenous delivery, perhaps with an infall flux as high as ~0.1 mol/km(2)/yr or 0.18 mmol/m(2) in a single impact. Formamide has recently been proposed as a single-carbon, prebiotic source of nucleobases and nucleic acids. This study suggests that a sufficient amount of NH2CHO could have been available for such chemistry.
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