Model organisms: Mouse models challenged.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Glucagon, Metabolic Dysfunction-Associated Steatotic Liver Disease and Amino Acids in Humans and Animals without Diabetes Mellitus-An Evidence Map.Life (Basel, Switzerland) · 2024
   Review
2. The Neglected Sibling: NLRP2 Inflammasome in the Nervous System.Aging and disease · 2024
   Review
3. NLRP3 Inflammasome's Activation in Acute and Chronic Brain Diseases-An Update on Pathogenetic Mechanisms and Therapeutic Perspectives with Respect to Other Inflammasomes.Biomedicines · 2023
   Review
4. Three-dimensional (3D) liver cell models - a tool for bridging the gap between animal studies and clinical trials when screening liver accumulation and toxicity of nanobiomaterials.Drug delivery and translational research · 2022
   Review
5. Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex.Nature communications · 2018
   Article
6. The Value of Comparative Animal Research: Krogh's Principle Facilitates Scientific Discoveries.Policy insights from the behavioral and brain sciences · 2018
   Article
7. Genomic responses in mouse models greatly mimic human inflammatory diseases.Proceedings of the National Academy of Sciences of the United States of America · 2015
   Article
8. New Metrics for Evaluating Viral Respiratory Pathogenesis.PloS one · 2015
   Article
9. Abandon the mouse research ship? Not just yet!Shock (Augusta, Ga.) · 2014
   Article
10. Pathophysiology of endotoxin tolerance: mechanisms and clinical consequences.Critical care (London, England) · 2013
    Review

Corrections and comments

• Comment on
  Genomic responses in mouse models poorly mimic human inflammatory diseases.2013

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.