Evidence map›Paper›PMID 23653854›Full record

ArticleCardiovascular psychiatry and neurology2013

Depression and cardiac disease: epidemiology, mechanisms, and diagnosis.

Jeff C Huffman, Christopher M Celano, Scott R Beach, Shweta R Motiwala, James L Januzzi

3 registry-linked trialsOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular psychiatry and neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 174 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
174citing papers in PubMed, 9 pooled it
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02621567 phase4completednot on this mapstarted 2016, after this paper: background citation

Bright Light Therapy Efficacy for Depressive Symptoms Following Cardiac Surgery or Acute Coronary Syndrome: Pilot Trial

TypeinterventionalSponsorMcGill UniversityRan2016 to 2017Enrolled15ConditionsDepressive Symptoms Post Cardiac Surgery or Post Acute Coronary SyndromeArmsBright Light Therapy Lamp, Modified Dim Lamp
NCT03863262 completednot on this mapstarted 2018, after this paper: background citation

Screening for Depression in cADiovasCular pAtients at a Tertiary Center in Trinidad.

TypeobservationalSponsorThe University of The West IndiesRan2018 to 2019Enrolled1,203ConditionsDepression
NCT03878160 nacompletednot on this mapstarted 2018, after this paper: background citation

Mindfulness-Based Cognitive Therapy Delivered Via Group Videoconferencing for Acute Coronary Syndrome Patients With Elevated Depression Symptoms

TypeinterventionalSponsorMassachusetts General HospitalRan2018 to 2020Enrolled27ConditionsAcute Coronary Syndrome, Depression, Myocardial Infarction, Unstable AnginaArmsIndividual Interview
3 · Its place in the literature

Who cites it

174 citing papers in PubMed, 9 syntheses or guidelines pooled it, 440 citations in OpenAlex.

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  17. Quality of life as predictor for the development of cardiac ischemia in high-risk asymptomatic diabetic patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
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114 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeff C HuffmanHarvard Medical School, Boston, MA 02114, USA ; Department of Psychiatry, Massachusetts General Hospital, Blake 11, 55 Fruit Street, Boston, MA 02114, USA.
Christopher M Celano
Scott R Beach
Shweta R Motiwala
James L Januzzi
Massachusetts General Hospital · USHarvard University · US

Funding

Developing a positive psychology intervention to improve cardiac health behaviorsR01HL113272 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HUFFMAN, JEFF C · 2013 to 2017
$2.6M
NHLBI NIH HHS R01 HL113272
6 · The paper itself

Abstract

In patients with cardiovascular disease (CVD), depression is common, persistent, and associated with worse health-related quality of life, recurrent cardiac events, and mortality. Both physiological and behavioral factors-including endothelial dysfunction, platelet abnormalities, inflammation, autonomic nervous system dysfunction, and reduced engagement in health-promoting activities-may link depression with adverse cardiac outcomes. Because of the potential impact of depression on quality of life and cardiac outcomes, the American Heart Association has recommended routine depression screening of all cardiac patients with the 2- and 9-item Patient Health Questionnaires. However, despite the availability of these easy-to-use screening tools and effective treatments, depression is underrecognized and undertreated in patients with CVD. In this paper, we review the literature on epidemiology, phenomenology, comorbid conditions, and risk factors for depression in cardiac disease. We outline the associations between depression and cardiac outcomes, as well as the mechanisms that may mediate these links. Finally, we discuss the evidence for and against routine depression screening in patients with CVD and make specific recommendations for when and how to assess for depression in this high-risk population.

Identifiers

PMID23653854
PMCPMC3638710
OpenAlexW2160660885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.