Evidence map›Paper›PMID 23653664›Full record

ArticleFuture virology2013

HIV-1 and the immune response to TB.

Naomi F Walker, Graeme Meintjes, Robert J Wilkinson

Open access · greenAbstract read
In one paragraph

Article in Future virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. A pilot metabolomics study of tuberculosis immune reconstitution inflammatory syndrome.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Naomi F WalkerInfectious Diseases & Immunity, Imperial College London, W12 0NN, UK ; Clinical Infectious Diseases Research Initiative, Institute of Infectious Diseases & Molecular Medicine, University of Cape Town, Observatory 7925, South Africa.
Graeme Meintjes
Robert J Wilkinson
Imperial College London · GBUniversity of Cape Town · ZAWellcome Centre for Infectious Diseases Research in Africa · ZA

Funding

South Africa Tuberculosis AIDS Training (SATBAT)U2RTW007370 · FIC · WITS HEALTH CONSORTIUM (PTY), LTD · PI MARTINSON, NEIL A · 2007 to 2011
$1.9M
South Africa Tuberculosis/AIDS TrainingU2RTW007373 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VAN DER HORST, CHARLES MICHAEL · 2007 to 2012
$1.4M
FIC NIH HHS U2R TW007370FIC NIH HHS U2R TW007373Wellcome Trust 088316
6 · The paper itself

Abstract

TB causes 1.4 million deaths annually. HIV-1 infection is the strongest risk factor for TB. The characteristic immunological effect of HIV is on CD4 cell count. However, the risk of TB is elevated in HIV-1 infected individuals even in the first few years after HIV acquisition and also after CD4 cell counts are restored with antiretroviral therapy. In this review, we examine features of the immune response to TB and how this is affected by HIV-1 infection and

Indexed as

antiretroviral therapyARTdiagnosisHIVimmunityimmunopathologyTBTB-associated immune reconstitution inflammatory syndromeTB-IRIStuberculosis

Identifiers

PMID23653664
PMCPMC3644063
OpenAlexW2139398845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.