ArticleThe Journal of clinical endocrinology and metabolism2013
Hip structural analysis in adolescent boys with anorexia nervosa and controls.
Article in The Journal of clinical endocrinology and metabolism, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Body composition in anorexia nervosa: Meta-analysis and meta-regression of cross-sectional and longitudinal studies.The International journal of eating disorders · 2019Pooled it
- State of the art systematic review of bone disease in anorexia nervosa.The International journal of eating disorders · 2016Pooled it
- To Evaluate the Effect of Pediatric Massage Combined with Comprehensive Management on Growth Parameters and Biochemical Indicators in Children with Short Stature.International journal of general medicine · 2025Article
- Loss of Bone Density in Patients with Anorexia Nervosa Food That Alone Will Not Cure.Nutrients · 2024Review
- Retrospective Analysis of Factors Associated with Fracture in 714 Patients with Polymyalgia Rheumatica.International journal of rheumatology · 2022Article
- Daily activity relates to not only femoral bone mineral density, but also hip structural analysis parameters: A cross-sectional observational study.Osteoporosis and sarcopenia · 2021Article
- Hip Structural Analysis Reveals Impaired Hip Geometry in Girls With Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2020Article
- Associations between exercise, bone mineral density, and body composition in adolescents with anorexia nervosa.Eating and weight disorders : EWD · 2019Article
- Anorexia Nervosa and Osteoporosis: Pathophysiology and Treatment.Journal of bone metabolism · 2019Review
- Bone mineral density and estimated hip strength in men with anorexia nervosa, atypical anorexia nervosa and avoidant/restrictive food intake disorder.Clinical endocrinology · 2019Article
- Differences in Bone Mineral Density and Hip Geometry in Trochanteric and Cervical Hip Fractures in Elderly Chinese Patients.Orthopaedic surgery · 2019Article
- Resting Energy Expenditure, Body Composition and Phase Angle in Anorectic, Ballet Dancers and Constitutionally Lean Males.Nutrients · 2019Article
- Anorexia Nervosa and Bone.Current opinion in endocrine and metabolic research · 2018Article
- Osteoporosis in Children with Chronic Illnesses: Diagnosis, Monitoring, and Treatment.Current osteoporosis reports · 2017Review
- Assessment of Sex Differences in Fracture Risk Among Patients With Anorexia Nervosa: A Population-Based Cohort Study Using The Health Improvement Network.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017Article
- Assessment of Sex Differences in Body Composition Among Adolescents With Anorexia Nervosa.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2017Article
- Assessment of sex differences in bone deficits among adolescents with anorexia nervosa.The International journal of eating disorders · 2017Article
- Skeletal complications of eating disorders.Metabolism: clinical and experimental · 2015Review
- Correlation between Parameters of Calcaneal Quantitative Ultrasound and Hip Structural Analysis in Osteoporotic Fracture Patients.PloS one · 2015Article
- Underweight, overweight, and pediatric bone fragility: impact and management.Current osteoporosis reports · 2014Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
contextWe have reported lower hip bone mineral density (BMD) in adolescent boys with anorexia nervosa (AN) compared with controls. Although studies have described bone structure in girls with AN, these data are not available for boys. Hip structural analysis (HSA) using dual-energy x-ray absorptiometry is a validated technique to assess hip geometry and strength while avoiding radiation associated with quantitative computed tomography.
objectiveWe hypothesized that boys with AN would have impaired hip structure/strength (assessed by HSA) compared with controls. DESIGN AND
settingWe conducted a cross-sectional study at a clinical research center. SUBJECTS AND
interventionWe used HSA techniques on hip dual-energy x-ray absorptiometry scans in 31 previously enrolled boys, 15 with AN and 16 normal-weight controls, 12 to 19 years old.
resultsAN boys had lower body mass index SD score (P < .0001), testosterone (P = .0005), and estradiol (P = .006) than controls. A larger proportion of AN boys had BMD Z-scores <-1 at the femoral neck (60% vs 12.5%, P = 0008). Using HSA, at the narrow neck and trochanter region, boys with AN had lower cross-sectional area (P = .03, 0.02) and cortical thickness (P = .02, 0.03). Buckling ratio at the trochanter region was higher in AN (P = .008). After controlling for age and height, subperiosteal width at the femoral shaft, cross-sectional moment of inertia (narrow neck and femoral shaft), and section modulus (all sites) were lower in AN. The strongest associations of HSA measures were observed with lean mass, testosterone, and estradiol. On multivariate analysis, lean mass remained associated with most HSA measures.
conclusionsBoys with AN have impaired hip geometric parameters, associated with lower lean mass.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.