Evidence map›Paper›PMID 23653302›Full record

ArticleEMBO molecular medicine2013

The final frontier -- crossing the blood-brain barrier.

William S Sly, Carole Vogler

Abstract read
In one paragraph

Article in EMBO molecular medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA.Acta crystallographica. Section D, Biological crystallography · 2014
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

William S SlyEdward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA. slyws@slu.edu
Carole Vogler

Funding

RECEPTOR MEDIATED TRANSPORT OF LYSOSOMAL ENZYMESR01GM034182 · NIGMS · SAINT LOUIS UNIVERSITY · PI SLY, WILLIAM S · 1985 to 2013
$4.9M
RECEPTOR-MEDIATED TRANSPORT OF LYSOSOMAL ENZYMESR37GM034182 · NIGMS · SAINT LOUIS UNIVERSITY · PI SLY, WILLIAM S · 1988 to 1997
–
NIGMS NIH HHS GM034182NIGMS NIH HHS R01 GM034182
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBlood-Brain BarrierBrainDependovirusDisease Models, AnimalEnzyme Replacement TherapyGenetic TherapyGenetic VectorsHumansHydrolasesLysosomal Storage DiseasesMucopolysaccharidosesReceptor, IGF Type 2TranscytosisHydrolasesN-sulfoglucosamine sulfohydrolaseReceptor, IGF Type 2

Identifiers

PMID23653302
PMCPMC3662309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.