ArticleEuropean journal of nuclear medicine and molecular imaging2013
High FDG activity in focal fat necrosis: a pitfall in interpretation of posttreatment PET/CT in patients with non-Hodgkin lymphoma.
Article in European journal of nuclear medicine and molecular imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 23 citations in OpenAlex.
- Musculoskeletal Pitfalls on Molecular Imaging Studies of Oncologic Patients: How to Stay Out of Trouble.Tomography (Ann Arbor, Mich.) · 2024Review
- Repeatability of metabolic tumor burden and lesion glycolysis between clinical readers.Frontiers in immunology · 2023Article
- Multimodality imaging of mediastinal masses and mimics.Mediastinum (Hong Kong, China) · 2023Review
- Fat necrosis after abdominal surgery: A pitfall in interpretation of FDG-PET/CT.European radiology · 2018Article
- How We Read Oncologic FDG PET/CT.Cancer imaging : the official publication of the International Cancer Imaging Society · 2016Review
- The acetabular fossa hot spot on 18F-FDG PET/CT: epidemiology, natural history, and proposed etiology.Skeletal radiology · 2015Article
- Explorative analyses on the value of interim PET for prediction of response in pediatric and adolescent non-Hodgkin lymphoma patients.EJNMMI research · 2013Article
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7 authors at 2 institutions in 1 country.
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Abstract
purposePET/CT has a major role in lymphoma imaging, but glycolytic activity in inflammatory processes can reduce specificity. In this study we evaluated restaging PET/CT findings in patients with non-Hodgkin lymphoma (NHL) and fat necrosis.
methodsWe identified 16 patients from 8,819 restaging FDG PET/CT scans with suspicion of or biopsy-proven fat necrosis on PET/CT.
resultsAll patients had NHL and demonstrated focal FDG-avid nodular change on CT with density higher than that of fat but lower than that of soft tissue. Histological confirmation was obtained in eight patients, with high GLUT-1 staining between necrotic tissue and organizing fat necrosis evident. Uptake resolved in four patients, and surveillance was continuing in four without relapse.
conclusionAlthough rare, identification of fat necrosis in patients with a solitary FDG-avid nodule after therapy is important and may lead to the avoidance of unnecessary interventions or treatment. Specific features on CT aid identification, whilst follow-up imaging can be helpful as the metabolic abnormality regresses with time.
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