ReviewGut microbes
Mobile genetic elements of the human gastrointestinal tract: potential for spread of antibiotic resistance genes.
Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05611866 (A Pilot Study of Fecal Microbiota Transplant), which is not on this map. Cited by 74 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study of Fecal Microbiota Transplant (FMT) and Its Effects in Patients With Crohn's Disease With Moderate-to-High Risk of Colonization of Adherent-Invasive E. Coli (AIEC)
Who cites it
74 citing papers in PubMed, 143 citations in OpenAlex.
- A network dynamical simulation model for the study of antibiotic resistance in microbial communities.Gut microbes · 2026Article
- Dietary regulation on gut resistome linked with microbial amino acid metabolism in pigs.Animal microbiome · 2026Article
- Probiotics and Fermented Foods in Human Nutrition.Molecules (Basel, Switzerland) · 2026Review
- Mobile Genetic Elements as Central Drivers of Antimicrobial Resistance: Molecular Mechanisms, Evolutionary Ecology, One Health Implications and Control Strategies.Antibiotics (Basel, Switzerland) · 2026Review
- Restaurant occupational exposure affects the profiles of oral and gut pathobiomes and resistomes.Frontiers in microbiology · 2026Article
- Metagenomic and metabolomic profiling in primary aldosteronism with coexisting obstructive sleep apnea.Frontiers in endocrinology · 2026Observational
- Whole Genome Sequence Analysis of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- The impact of anthropogenic activities on antimicrobial and heavy metal resistance in aquatic environments.Applied and environmental microbiology · 2025Article
- Comparison of phage and plasmid populations in the gut microbiota between Parkinson's disease patients and controls.Scientific reports · 2025Article
- Antibiotic resistance dynamics of some common probioticVeterinary research forum : an international quarterly journal · 2025Article
- In Vitro Screening of Bacterial Isolates From Dairy Products for Probiotic Properties and Other Health-Promoting Attributes.Food science & nutrition · 2024Article
- Dietary apidaecin Api-PR19 addition enhances growth performance by regulating gut health and microbiota in broilers.Animal bioscience · 2024Article
- Accounting for the health risk of probiotics.Heliyon · 2024Review
- A metagenomic analysis for combination therapy of multiple classes of antibiotics on the prevention of the spread of antibiotic-resistant genes.Gut microbes · 2023Article
- Promotion of plasmid maintenance by heterogeneous partitioning of microbial communities.Cell systems · 2023Article
- An Insight into the Exploration of Antibiotic Resistance Genes in Calorie Restricted Diet Fed Mice.Nutrients · 2023Article
- Toxin-linked mobile genetic elements in major enteric bacterial pathogens.Gut microbiome (Cambridge, England) · 2023Review
- Diverse functional genes harboured in extracellular vesicles from environmental and human microbiota.Journal of extracellular vesicles · 2022Article
- Antibiotic resistance surveillance ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022Article
- Nanotechnology for research and treatment of the intestine.Journal of nanobiotechnology · 2022Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human intestine is an important location for horizontal gene transfer (HGT) due to the presence of a densely populated community of microorganisms which are essential to the health of the human superorganism. HGT in this niche has the potential to influence the evolution of members of this microbial community and to mediate the spread of antibiotic resistance genes from commensal organisms to potential pathogens. Recent culture-independent techniques and metagenomic studies have provided an insight into the distribution of mobile genetic elements (MGEs) and the extent of HGT in the human gastrointestinal tract. In this mini-review, we explore the current knowledge of mobile genetic elements in the gastrointestinal tract, the progress of research into the distribution of antibiotic resistance genes in the gut and the potential role of MGEs in the spread of antibiotic resistance. In the face of reduced treatment options for many clinical infections, understanding environmental and commensal antibiotic resistance and spread is critical to the future development of meaningful and long lasting anti-microbial therapies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.