ArticleEnvironmental health perspectives2013
Measures of thyroid function among Belarusian children and adolescents exposed to iodine-131 from the accident at the Chernobyl nuclear plant.
Article in Environmental health perspectives, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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28 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Somatic health effects of Chernobyl: 30 years on.European journal of epidemiology · 2017Pooled it
- Validation of established thyroid ultrasound volume norms in a Chernobyl cohort.European thyroid journal · 2025Article
- Identification of Thyroid Genes Whose Expression Is Altered by Neonatal Irradiation in Rats.International journal of molecular sciences · 2025Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- The effect of exposure on cattle thyroid after the Fukushima Daiichi nuclear power plant accident.Scientific reports · 2022Article
- Association between exposure to radioactive iodine after the Chernobyl accident and thyroid volume in Belarus 10-15 years later.Environmental health : a global access science source · 2022Article
- Hypothyroidism after radiation exposure: brief narrative review.Journal of neural transmission (Vienna, Austria : 1996) · 2020Review
- Belarusian in utero cohort: A new opportunity to evaluate the health effects of prenatal and early-life exposure to ionising radiation.Journal of radiological protection : official journal of the Society for Radiological Protection · 2020Article
- Thyroid Dose Estimates for a Cohort of Belarusian Persons Exposed in Utero and During Early Life to Chernobyl Fallout.Health physics · 2020Article
- Radiation Exposure to the Thyroid After the Chernobyl Accident.Frontiers in endocrinology · 2020Review
- Thyroid nodule prevalence among women in areas of high natural background radiation, Karunagappally, Kerala, India.Endocrine · 2020Article
- Article
- Hyperthyroidism After Radiation Therapy for Childhood Cancer: A Report from the Childhood Cancer Survivor Study.International journal of radiation oncology, biology, physics · 2019Article
- Influence of the external and internal radioactive contamination of the body and the clothes on the results of the thyroidalRadiation and environmental biophysics · 2019Article
- Inflammatory disease and C-reactive protein in relation to therapeutic ionising radiation exposure in the US Radiologic Technologists.Scientific reports · 2019Article
- Mild Hypothyroidism in Childhood: Who, When, and How Should Be Treated?Journal of the Endocrine Society · 2018Review
- Article
- Radiation-related thyroid autoimmunity and dysfunction.Journal of radiation research · 2018Review
- Is Graves' disease a primary immunodeficiency? New immunological perspectives on an endocrine disease.BMC medicine · 2017Review
- Factors associated with serum thyroglobulin in a Ukrainian cohort exposed to iodine-131 from the accident at the Chernobyl Nuclear Plant.Environmental research · 2017Article
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17 authors at 7 institutions in 3 countries.
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Abstract
backgroundThyroid dysfunction after exposure to low or moderate doses of radioactive iodine-131 (131I) at a young age is a public health concern. However, quantitative data are sparse concerning 131I-related risk of these common diseases.
objectiveOur goal was to assess the prevalence of thyroid dysfunction in association with 131I exposure during childhood (≤ 18 years) due to fallout from the Chernobyl accident.
methodsWe conducted a cross-sectional analysis of hypothyroidism, hyperthyroidism, autoimmune thyroiditis (AIT), serum concentrations of thyroid-stimulating hormone (TSH), and autoantibodies to thyroperoxidase (ATPO) in relation to measurement-based 131I dose estimates in a Belarusian cohort of 10,827 individuals screened for various thyroid diseases.
resultsMean age at exposure (± SD) was 8.2 ± 5.0 years. Mean (median) estimated 131I thyroid dose was 0.54 (0.23) Gy (range, 0.001-26.6 Gy). We found significant positive associations of 131I dose with hypothyroidism (mainly subclinical and antibody-negative) and serum TSH concentration. The excess odds ratio per 1 Gy for hypothyroidism was 0.34 (95% CI: 0.15, 0.62) and varied significantly by age at exposure and at examination, presence of goiter, and urban/rural residency. We found no evidence of positive associations with antibody-positive hypothyroidism, hyperthyroidism, AIT, or elevated ATPO.
conclusionsThe association between 131I dose and hypothyroidism in the Belarusian cohort is consistent with that previously reported for a Ukrainian cohort and strengthens evidence of the effect of environmental 131I exposure during childhood on hypothyroidism, but not other thyroid outcomes.
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