ArticleFEBS open bio2011
Diadenosine polyphosphates (Ap3A and Ap4A) behave as alarmones triggering the synthesis of enzymes of the phenylpropanoid pathway in Arabidopsis thaliana.
Article in FEBS open bio, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates.FEBS letters · 2026Review
- Using native and synthetic genes to disrupt inositol pyrophosphates and phosphate accumulation in plants.Plant physiology · 2024Article
- The Plasma Membrane Purinoreceptor P2K1/DORN1 Is Essential in Stomatal Closure Evoked by Extracellular Diadenosine Tetraphosphate (ApInternational journal of molecular sciences · 2023Article
- Article
- The Rosetta Stone Hypothesis-Based Interaction of the Tumor Suppressor Proteins Nit1 and Fhit.Cells · 2023Article
- Nucleoside 5'-Phosphoramidates Control the Phenylpropanoid Pathway inInternational journal of molecular sciences · 2021Article
- Transcriptomic Changes in Internode Explants of Stinging Nettle during Callogenesis.International journal of molecular sciences · 2021Article
- In Vitro Response ofCells · 2021Article
- Integrated Analysis of the Transcriptome and Metabolome ofInternational journal of molecular sciences · 2020Article
- Review
- Re-evaluation of Diadenosine Tetraphosphate (ApFrontiers in molecular biosciences · 2020Review
- Emerging strategies for the identification of protein-metabolite interactions.Journal of experimental botany · 2019Article
- Five years on -FEBS open bio · 2016Article
- The invA gene of Brucella melitensis is involved in intracellular invasion and is required to establish infection in a mouse model.Virulence · 2014Article
- Chlamydia trachomatis CT771 (nudH) is an asymmetric Ap4A hydrolase.Biochemistry · 2014Article
- Diadenosine polyphosphates (Ap3A and Ap4A) behave as alarmones triggering the synthesis of enzymes of the phenylpropanoid pathway in Arabidopsis thaliana.FEBS open bio · 2011Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is known that cells under stress accumulate various dinucleoside polyphosphates, compounds suggested to function as alarmones. In plants, the phenylpropanoid pathways yield metabolites protecting these organisms against various types of stress. Observations reported in this communication link these two phenomena and provide an example of a metabolic "addressee" for an "alarm" signaled by diadenosine triphosphate (Ap3A) or diadenosine tetraphosphate (Ap4A). In response to added Ap3A or Ap4A, seedlings of Arabidopsis thaliana incubated in full nutrition medium increased both the expression of the genes for and the specific activity of phenylalanine ammonia-lyase and 4-coumarate:coenzyme A ligase, enzymes that control the beginning of the phenylpropanoid pathway. Neither adenine mononucleotides (AMP, ADP or ATP) nor adenosine evoked such effects. Reactions catalyzed in vitro by these enzymes were not affected by Ap3A or Ap4A.
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