Trial reportPediatrics2013
Effectiveness of decision support for families, clinicians, or both on HPV vaccine receipt.
Trial report in Pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 126 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
HPV Vaccination: An Investigation of Physician Reminders and Recommendation Scripts
HPV Vaccination: Evaluation of Reminder Prompts for Doses 2 & 3
Who cites it
126 citing papers in PubMed, 13 syntheses or guidelines pooled it, 214 citations in OpenAlex.
- Exploring equity in audit and feedback trials: Secondary analysis of a systematic review.PloS one · 2026Pooled it
- Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care.The Cochrane database of systematic reviews · 2025Pooled it
- Audit and feedback: effects on professional practice.The Cochrane database of systematic reviews · 2025Pooled it
- Electronic Health Record Nudges and Health Care Quality and Outcomes in Primary Care: A Systematic Review.JAMA network open · 2024Pooled it
- A systematic review and meta-analysis of strategies to promote vaccination uptake.Nature human behaviour · 2024Pooled it
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024Pooled it
- Pooled it
- Strategies to overcome vaccine hesitancy: a systematic review.Systematic reviews · 2022Pooled it
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2017Pooled it
- Interventions to increase HPV vaccination coverage: A systematic review.Human vaccines & immunotherapeutics · 2016Pooled it
- Practice- and Community-Based Interventions to Increase Human Papillomavirus Vaccine Coverage: A Systematic Review.JAMA pediatrics · 2015Pooled it
- The effects of on-screen, point of care computer reminders on processes and outcomes of care.The Cochrane database of systematic reviews · 2009Pooled it
- Costs of Interventions to Increase Vaccination Coverage Among Children in the United States: A Systematic Review.Academic pediatricsPooled it
- TeenVac.org: A Mobile Web App to Improve Human Papillomavirus Vaccine Uptake for Adolescent Boys.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Trial
- Multilevel Intervention and Human Papillomavirus Vaccination Disparities: A Secondary Analysis of a Cluster Randomized Trial.JAMA network open · 2025Trial
- Human Papillomavirus vaccination clinical decision support for young adults in an upper midwestern healthcare system: a clinic cluster-randomized control trial.Human vaccines & immunotherapeutics · 2022Trial
- Impact of a Multi-Level, Multi-Component, System Intervention on HPV Vaccination in a Federally Qualified Health Center.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Trial
- Coaching and Communication Training for HPV Vaccination: A Cluster Randomized Trial.Pediatrics · 2022Trial
- Centralized Reminder/Recall for Human Papillomavirus Vaccination: Findings From Two States-A Randomized Clinical Trial.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2021Trial
- Parent eReferral to Tobacco Quitline: A Pragmatic Randomized Trial in Pediatric Primary Care.American journal of preventive medicine · 2019Trial
66 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo improve human papillomavirus (HPV) vaccination rates, we studied the effectiveness of targeting automated decision support to families, clinicians, or both.
methodsTwenty-two primary care practices were cluster-randomized to receive a 3-part clinician-focused intervention (education, electronic health record-based alerts, and audit and feedback) or none. Overall, 22, 486 girls aged 11 to 17 years due for HPV vaccine dose 1, 2, or 3 were randomly assigned within each practice to receive family-focused decision support with educational telephone calls. Randomization established 4 groups: family-focused, clinician-focused, combined, and no intervention. We measured decision support effectiveness by final vaccination rates and time to vaccine receipt, standardized for covariates and limited to those having received the previous dose for HPV #2 and 3. The 1-year study began in May 2010.
resultsFinal vaccination rates for HPV #1, 2, and 3 were 16%, 65%, and 63% among controls. The combined intervention increased vaccination rates by 9, 8, and 13 percentage points, respectively. The control group achieved 15% vaccination for HPV #1 and 50% vaccination for HPV #2 and 3 after 318, 178, and 215 days. The combined intervention significantly accelerated vaccination by 151, 68, and 93 days. The clinician-focused intervention was more effective than the family-focused intervention for HPV #1, but less effective for HPV #2 and 3.
conclusionsA clinician-focused intervention was most effective for initiating the HPV vaccination series, whereas a family-focused intervention promoted completion. Decision support directed at both clinicians and families most effectively promotes HPV vaccine series receipt.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.