Evidence map›Paper›PMID 23650175›Full record

ArticleAntimicrobial agents and chemotherapy2013

The comprehensive antibiotic resistance database.

Andrew G McArthur, Nicholas Waglechner, Fazmin Nizam, Austin Yan, Marisa A Azad, Alison J Baylay, Kirandeep Bhullar, Marc J Canova, Gianfranco De Pascale, Linda Ejim and 17 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,224 papers.

0numbers the graph read from it
0cells of the map it votes in
1,224citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,224 citing papers in PubMed.

  1. Article
  2. Article
  3. Genomic divergence and phenotypic heterogeneity ofApplied and environmental microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Effect ofMicrobiology spectrum · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Comparative Genomics-Based Evaluation ofJournal of microbiology and biotechnology · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

1,164 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Andrew G McArthurM.G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
Nicholas Waglechner
Fazmin Nizam
Austin Yan
Marisa A Azad
Alison J Baylay
Kirandeep Bhullar
Marc J Canova
Gianfranco De Pascale
Linda Ejim
Lindsay Kalan
Andrew M King
Kalinka Koteva
Mariya Morar
Michael R Mulvey
Jonathan S O'Brien
Andrew C Pawlowski
Laura J V Piddock
Peter Spanogiannopoulos
Arlene D Sutherland
Irene Tang
Patricia L Taylor
Maulik Thaker
Wenliang Wang
Marie Yan
Tennison Yu
Gerard D Wright

Funding

Canadian Institutes of Health ResearchMedical Research Council
6 · The paper itself

Abstract

The field of antibiotic drug discovery and the monitoring of new antibiotic resistance elements have yet to fully exploit the power of the genome revolution. Despite the fact that the first genomes sequenced of free living organisms were those of bacteria, there have been few specialized bioinformatic tools developed to mine the growing amount of genomic data associated with pathogens. In particular, there are few tools to study the genetics and genomics of antibiotic resistance and how it impacts bacterial populations, ecology, and the clinic. We have initiated development of such tools in the form of the Comprehensive Antibiotic Research Database (CARD; http://arpcard.mcmaster.ca). The CARD integrates disparate molecular and sequence data, provides a unique organizing principle in the form of the Antibiotic Resistance Ontology (ARO), and can quickly identify putative antibiotic resistance genes in new unannotated genome sequences. This unique platform provides an informatic tool that bridges antibiotic resistance concerns in health care, agriculture, and the environment.

Indexed as

Anti-Infective AgentsDatabases, GeneticGenes, BacterialBase SequenceComputational BiologyDrug Resistance, MicrobialGenome, BacterialInternetUser-Computer InterfaceAnti-Infective Agents

Identifiers

PMID23650175
PMCPMC3697360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.