ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2013
Diagnostic measures for sarcopenia and bone mineral density.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2019Pooled it
- Differences in handgrip strength protocols to identify sarcopenia and frailty - a systematic review.BMC geriatrics · 2017Pooled it
- Pooled it
- Resistance training with or without nutritional supplementation showed no influence on muscle thickness in old-institutionalized adults: a secondary analysis of the Vienna Active Ageing Study.European journal of physical and rehabilitation medicine · 2022Trial
- Change in maximal fat oxidation in response to different regimes of periodized high-intensity interval training (HIIT).European journal of applied physiology · 2017Trial
- Association between myosteatosis and bone mineral density in postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Health outcomes of sarcopenia: a consensus report by the outcome working group of the Global Leadership Initiative in Sarcopenia (GLIS).Aging clinical and experimental research · 2025Review
- Mendelian randomization study on association between grip strength and BMD in different age groups.Journal of bone and mineral metabolism · 2024Article
- Correlation study between bone metabolic markers, bone mineral density, and sarcopenia.Journal of endocrinological investigation · 2024Article
- How disability severity is associated with changes in physical activity and inactivity from adolescence to young adulthood.Archives of public health = Archives belges de sante publique · 2023Article
- Precedence of Bone Loss Accompanied with Changes in Body Composition and Body Fat Distribution in Patients with Type 2 Diabetes Mellitus.Journal of diabetes research · 2023Article
- Relation between adipose tissue and the musculoskeletal unit in a group of postmenopausal women.Przeglad menopauzalny = Menopause review · 2022Article
- Integrating Muscle Health in Predicting the Risk of Asymptomatic Vertebral Fracture in Older Adults.Journal of clinical medicine · 2021Article
- Body composition and bone status in relation to microvascular damage in systemic sclerosis patients.Journal of endocrinological investigation · 2021Article
- Factors associated with measures of sarcopenia in pre and postmenopausal women.BMC women's health · 2021Article
- Association of Low Bone Mass with Decreased Skeletal Muscle Mass: A Cross-Sectional Study of Community-Dwelling Older Women.Healthcare (Basel, Switzerland) · 2020Article
- Creatinine to Cystatin C Ratio as a Marker of Bone Property in Older Adults: The J-SHIPP Study.The journal of nutrition, health & aging · 2020Article
- The Association between Osteoporosis and Grip Strength and Skeletal Muscle Mass in Community-Dwelling Older Women.International journal of environmental research and public health · 2019Article
- Skeletal muscle reference for Chinese children and adolescents.Journal of cachexia, sarcopenia and muscle · 2019Article
- Accuracy and prognostic ability of the SARC-F questionnaire and Ishii's score in the screening of sarcopenia in geriatric inpatients.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
summaryCurrently used diagnostic measures for sarcopenia utilize different measures of muscle mass, muscle strength, and physical performance. These diagnostic measures associate differently to bone mineral density (BMD), as an example of muscle-related clinical outcome. These differences should be taken into account when studying sarcopenia.
introductionDiagnostic measures for sarcopenia utilize different measures of muscle mass, muscle strength, and physical performance. To understand differences between these measures, we determined the association with respect to whole body BMD, as an example of muscle-related clinical outcome.
methodsIn the European cross-sectional study MYOAGE, 178 young (18-30 years) and 274 healthy old participants (69-81 years) were recruited. Body composition and BMD were evaluated using dual-energy X-ray densitometry. Diagnostic measures for sarcopenia were composed of lean mass as percentage of body mass, appendicular lean mass (ALM) as percentage of body mass, ALM divided by height squared (ALM/height(2)), knee extension torque, grip strength, walking speed, and Timed Up and Go test (TUG). Linear regression models were stratified for sex and age and adjusted for age and country, and body composition in separate models.
resultsLean mass and ALM/height(2) were positively associated with BMD (P < 0.001). Significance remained in all sex and age subgroups after further adjustment for fat mass, except in old women. Lean mass percentage and ALM percentage were inversely associated with BMD in old women (P < 0.001). These inverse associations disappeared after adjustment for body mass. Knee extension torque and handgrip strength were positively associated with BMD in all subgroups (P < 0.01), except in old women. Walking speed and TUG were not related to BMD.
conclusionsThe associations between diagnostic measures of sarcopenia and BMD as an example of muscle-related outcome vary widely. Differences between diagnostic measures should be taken into account when studying sarcopenia.
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