Evidence map›Paper›PMID 23649720›Full record

ReviewMovement disorders : official journal of the Movement Disorder Society2013

Phenomenology and classification of dystonia: a consensus update.

Alberto Albanese, Kailash Bhatia, Susan B Bressman, Mahlon R Delong, Stanley Fahn, Victor S C Fung, Mark Hallett, Joseph Jankovic, Hyder A Jinnah, Christine Klein and 3 more

7 registry-linked trialsAbstract readReviewConsensus Statement
In one paragraph

Review in Movement disorders : official journal of the Movement Disorder Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 1,012 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,012citing papers in PubMed, 10 pooled it
82.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03247868 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Multimodal Treatment of Cervical Dystonia With Botulinum Toxin Injections Associated With a Sensory-motor Perceptive Rehabilitation Integrated Approach (SPRInt) Based on Motor Learning Techniques

TypeinterventionalSponsorFondazione Don Carlo Gnocchi ETSRan2016 to 2018Enrolled20ConditionsCervical Dystonia,PrimaryArmsBotulinum Toxin+SPRInt
NCT03263000 terminatednot on this mapstarted 2017, after this paper: background citation

Study of the Photic Blink Reflex in Patients With Blepharospasm and Increased Blinking

TypeobservationalSponsorNational Institute of Neurological Disorders and Stroke (NINDS)Ran2017 to 2019Enrolled17ConditionsBlepharospasm
NCT03938363 nacompletednot on this mapstarted 2019, after this paper: background citation

Analyse de la Marche de Patients Atteints de Dystonie Focale Avant et après Traitement Par Toxine Botulique

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2019 to 2022Enrolled40ConditionsCervical Dystonia, Primary, BlepharospasmArmsTreadmill, Botulinum Toxin injection, Severity scale of the disease
NCT05884528 completednot on this mapstarted 2023, after this paper: background citation

Assessment of Long-term Clinical Response to BoNT in Cervical Dystonia - Real-world Evidence of LongevitY of Botulinum Toxin in Cervical Dystonia

TypeobservationalSponsorMerz Therapeutics GmbHRan2023 to 2024Enrolled270ConditionsCervical DystoniaArmsCC BoNT/A, CF BoNT/A, CF to CC BoNT/A, CC to CF BoNT/A
NCT06328790 unknown statusnot on this mapstarted 2023, after this paper: background citation

A Window Into the Mind-brain-body Interplay: Development of Diagnostic, Prognostic Biomarkers and Rehabilitation Strategies in Functional Motor Disorders

TypeobservationalSponsorMichele Tinazzi, MD, PhDRan2023 to 2025Enrolled450ConditionsFunctional Motor DisordersArmsMultidisciplinary Rehabilitation Training, Cross-sectional study on patients with FMD and patients with structural/organic diseases, Cross-sectional study on patients with FMD and healthy controls (HC)
NCT07014384 nacompletednot on this mapstarted 2024, after this paper: background citation

A Randomized, Sham-controlled Study of Cerebellar Transcranial Direct Current Stimulation (tDCS) and Its Effects on the Neurophysiological Properties of the Sensorimotor Network and Motor Symptom Severity in Patients With Isolated Cervical Dystonia (CD)

TypeinterventionalSponsorUniversitätsklinikum Hamburg-EppendorfRan2024 to 2026Enrolled15ConditionsIsolated Cervical DystoniaArmsAnodal and cathodal ctDCS, Sham stimulation
NCT07233993 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Randomised, Cross-over, Double-blind, Sham-Controlled Superiority Trial of UltraSound-Guided Versus Non-Ultrasound-Guided Botulinum TOxin Injections in Cervical DYstonia

TypeinterventionalSponsorFondazione I.R.C.C.S. Istituto Neurologico Carlo BestaRan2025 to 2027Enrolled100ConditionsIdiopathic Cervical DystoniaArmsUltrasound-guided botulinum toxin injection, Non-ultrasound-guided botulinum toxin injection
3 · Its place in the literature

Who cites it

1,012 citing papers in PubMed, 10 syntheses or guidelines pooled it, 2,210 citations in OpenAlex.

  1. Managing Dystonia in Partington Syndrome.Movement disorders clinical practice · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. The epidemiology and phenomenology of non-antipsychotic-induced dystonia: a hybrid systematic-narrative review.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Guideline
  11. Trial
  12. Trial
  13. Trial
  14. Long-Term Outcomes on Pallidal Neurostimulation for Dystonia: A Controlled, Prospective 10-Year Follow-Up.Movement disorders : official journal of the Movement Disorder Society · 2025
    Trial
  15. Diagnostic approach and treatment options for myoclonus.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. Optimal physiotherapy management strategies for cervical dystonia: an international Delphi study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  20. Article

952 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 6 countries.

Alberto AlbaneseDepartment of Neurology, Catholic University, Milan, Italy. alberto.albanese@unicatt.it
Kailash Bhatia
Susan B Bressman
Mahlon R Delong
Stanley Fahn
Victor S C Fung
Mark Hallett
Joseph Jankovic
Hyder A Jinnah
Christine Klein
Anthony E Lang
Jonathan W Mink
Jan K Teller
Emory University · USBaylor College of Medicine · USColumbia University · USDystonia Medical Research Foundation · USMount Sinai Beth Israel · USNational Institutes of Health · USSobell House · GBThe University of Sydney · AUUniversità Cattolica del Sacro Cuore · ITUniversity of Lübeck · DEUniversity of Rochester · USUniversity of Toronto · CA

Funding

Pathophysiology of Basal Ganglia DisordersZIANS003031 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI HALLETT, MARK · 2009 to 2023
$22.7M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
Intramural NIH HHS ZIA NS003031NCATS NIH HHS U54 TR001456
6 · The paper itself

Abstract

This report describes the consensus outcome of an international panel consisting of investigators with years of experience in this field that reviewed the definition and classification of dystonia. Agreement was obtained based on a consensus development methodology during 3 in-person meetings and manuscript review by mail. Dystonia is defined as a movement disorder characterized by sustained or intermittent muscle contractions causing abnormal, often repetitive, movements, postures, or both. Dystonic movements are typically patterned and twisting, and may be tremulous. Dystonia is often initiated or worsened by voluntary action and associated with overflow muscle activation. Dystonia is classified along 2 axes: clinical characteristics, including age at onset, body distribution, temporal pattern and associated features (additional movement disorders or neurological features); and etiology, which includes nervous system pathology and inheritance. The clinical characteristics fall into several specific dystonia syndromes that help to guide diagnosis and treatment. We provide here a new general definition of dystonia and propose a new classification. We encourage clinicians and researchers to use these innovative definition and classification and test them in the clinical setting on a variety of patients with dystonia. © 2013 Movement Disorder Society.

Indexed as

International CooperationAge of OnsetDatabases, FactualDystoniaHumansNervous Systemclassificationdefinitiondystonia

Identifiers

PMID23649720
PMCPMC3729880
OpenAlexW2131134103

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

and 1 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.