Evidence map›Paper›PMID 23649401›Full record

ArticleSkeletal radiology2013

Schwannoma in neurofibromatosis type 1: a pitfall for detecting malignancy by metabolic imaging.

Shivani Ahlawat, Jaishri Blakeley, Elizabeth Montgomery, Rathan M Subramaniam, Allan Belzberg, Laura M Fayad

Abstract readCase Reports
In one paragraph

Article in Skeletal radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. C-Fiber Loss as a Possible Cause of Neuropathic Pain in Schwannomatosis.International journal of molecular sciences · 2020
    Article
  8. Cancer of the Peripheral Nerve in Neurofibromatosis Type 1.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2017
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shivani AhlawatThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 North Wolfe Street, Baltimore, MD 21287, USA. sahlawa1@jhmi.edu
Jaishri Blakeley
Elizabeth Montgomery
Rathan M Subramaniam
Allan Belzberg
Laura M Fayad
Johns Hopkins Hospital · USJohns Hopkins Medicine · USJohns Hopkins University · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI WILLIAM George NELSON · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

Neurofibromatosis type 1 (NF1) is a neurocutaneous syndrome characterized by the development of multiple peripheral nerve sheath tumors, the majority of which are benign neurofibromas. However, malignant peripheral nerve sheath tumors (MPNSTs) occur with a 10 % lifetime risk in patients with NF1, often developing within a neurofibroma. When clinical suspicion for an MPNST arises, imaging with FDG PET and MRI is performed to characterize a peripheral tumor for potential malignancy. In this report, we describe a patient with NF-1 who had two peripheral tumors with similar features by PET, both suspicious for MPNST, but differing features by MRI, one of which was subsequently determined to be an MPNST and the second to be a schwannoma.

Indexed as

Fluorodeoxyglucose F18Diagnosis, DifferentialDiagnostic ErrorsHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasms, Multiple PrimaryNeurofibromatosis 1Positron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificitySoft Tissue NeoplasmsFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID23649401
PMCPMC3991125
OpenAlexW1998917215

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.