ArticlePhotosynthesis research2013
Kinetics and functional diversity among the five members of the NADP-malic enzyme family from Zea mays, a C4 species.
Article in Photosynthesis research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 34 citations in OpenAlex.
- A milestone in C4 carbon concentration mechanism evolution: structural remodeling of NADP-malic enzyme in Poaceae.Molecular biology and evolution · 2026Article
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- NAD(H) and NADP(H) in plants and mammals.Molecular plant · 2025Review
- Identification of the cassavaFrontiers in plant science · 2025Article
- Leaf transcriptomes from C3, C3-C4 intermediate, and C4Neurachne species give insights into C4 photosynthesis evolution.Plant physiology · 2024Article
- Genomic and Transcriptomic Insights into the Evolution of C4 Photosynthesis in Grasses.Genome biology and evolution · 2024Article
- Overexpression of chloroplastic Zea mays NADP-malic enzyme (ZmNADP-ME) confers tolerance to salt stress in Arabidopsis thaliana.Photosynthesis research · 2023Article
- Epi-Brassinolide RegulatesInternational journal of molecular sciences · 2023Article
- ChloroplasticPlants (Basel, Switzerland) · 2021Article
- Posttranslational Modification of the NADP-Malic Enzyme Involved in CThe Plant cell · 2019Article
- The intracellular distribution of inorganic carbon fixing enzymes does not support the presence of a C4 pathway in the diatom Phaeodactylum tricornutum.Photosynthesis research · 2018Article
- Synergistic Binding of bHLH Transcription Factors to the Promoter of the Maize NADP-ME Gene Used in C4 Photosynthesis Is Based on an Ancient Code Found in the Ancestral C3 State.Molecular biology and evolution · 2018Article
- Improved water use efficiency and shorter life cycle of Nicotiana tabacum due to modification of guard and vascular companion cells.Scientific reports · 2018Article
- Chimeric Structure of Plant Malic Enzyme Family: Different Evolutionary Scenarios for NAD- and NADP-Dependent Isoforms.Frontiers in plant science · 2018Article
- NADP-Dependent Malic Enzyme 1 Participates in the Abscisic Acid Response inFrontiers in plant science · 2018Article
- Strategies and tools to improve crop productivity by targeting photosynthesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
- Systems biology and metabolic modelling unveils limitations to polyhydroxybutyrate accumulation in sugarcane leaves; lessons for C4 engineering.Plant biotechnology journal · 2016Article
- Differential Contribution of Malic Enzymes during Soybean and Castor Seeds Maturation.PloS one · 2016Article
- Biochemical approaches to C4 photosynthesis evolution studies: the case of malic enzymes decarboxylases.Photosynthesis research · 2013Review
- Parallel recruitment of multiple genes into c4 photosynthesis.Genome biology and evolution · 2013Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
NADP-malic enzyme (NADP-ME) is involved in different metabolic pathways in several organisms due to the relevant physiological functions of the substrates and products of its reaction. In plants, it is one of the most important proteins that were recruited to fulfil key roles in C4 photosynthesis. Recent advances in genomics allowed the characterization of the complete set of NADP-ME genes from some C3 species, as Arabidopsis thaliana and Oryza sativa; however, the characterization of the complete NADP-ME family from a C4 species has not been performed yet. In this study, while taking advantage of the complete Zea mays genome sequence recently released, the characterization of the whole NADP-ME family is presented. The maize NADP-ME family is composed of five genes, two encoding plastidic NADP-MEs (ZmC4- and ZmnonC4-NADP-ME), and three cytosolic enzymes (Zmcyt1-, Zmcyt2-, and Zmcyt3-NADP-ME). The results presented clearly show that each maize NADP-ME displays particular organ distribution, response to stress stimuli, and differential biochemical properties. Phylogenetic footprinting studies performed with the NADP-MEs from several grasses, indicate that four members of the maize NADP-ME family share conserved transcription factor binding motifs with their orthologs, indicating conserved physiological functions for these genes in monocots. Based on the results obtained in this study, and considering the biochemical plasticity shown by the NADP-ME, it is discussed the relevance of the presence of a multigene family, in which each member encodes an isoform with particular biochemical properties, in the evolution of the C4 NADP-ME, improved to fulfil the requirements for an efficient C4 mechanism.
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