Evidence map›Paper›PMID 23647258›Full record

ArticleJournal of the American Geriatrics Society2013

Metabolic syndrome and hemoglobin levels in elderly adults: the Invecchiare in Chianti Study.

Alice Laudisio, Stefania Bandinelli, Antonella Gemma, Luigi Ferrucci, Raffaele Antonelli Incalzi

Abstract readComparative Study
In one paragraph

Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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  8. Hemoglobin level and lipoprotein particle size.Lipids in health and disease · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Alice LaudisioGeriatrics Section, Campus Bio-Medico University, Rome, Italy.
Stefania BandinelliGeriatric Rehabilitation Unit, Azienda Sanitaria di Firenze, Florence, Italy.
Antonella GemmaUOS Accesso e Presa in Carico Assistenziale, Azienda Sanitaria Locale Roma E, Rome, Italy.
Luigi FerrucciLongitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland.
Raffaele Antonelli IncalziGeriatrics Section, Campus Bio-Medico University, Rome, Italy.
Università Campus Bio-Medico · ITAzienda Sanitaria di Firenze · ITAzienda Sanitaria Locale Roma 3 · ITNational Institute on Aging · US

Funding

The InChianti StudyZIAAG001050 · NIA · NATIONAL INSTITUTE ON AGING · PI FERRUCCI, LUIGI · 2009 to 2025
$2.1M
HISPANIC SECONDARY STROKE PREVENTION INITIATIVER01MD009164 · NIMHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN · 2014 to 2018
$1.9M
THE INCHIANTI FOLLOW-UP STUDY-260012111N01AG012111 · NIA · ITALIAN NATL. INST. ON AGING · 2003 to 2003
–
NIA NIH HHS N01-AG-5-0002NIA NIH HHS N01 AG821336NIA NIH HHS N01 AG916413NIA NIH HHS N1-AG-1-1NIA NIH HHS N1-AG-1-2111NIMHD NIH HHS 263 MD 821336NIMHD NIH HHS 263 MD 9164NIMHD NIH HHS R01 MD009164
6 · The paper itself

Abstract

objectivesTo assess the association between metabolic syndrome (MetS) and hemoglobin levels in older adults.

designThe Invecchiare in Chianti (InCHIANTI) Study, a cohort study with a 6-year follow-up.

settingTuscany, Italy.

participantsAdults aged 65 and older (N = 1,036). MEASUREMENTS: MetS was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III criteria. The adjusted association between baseline hemoglobin and MetS was assessed using multivariable linear regression with hemoglobin as a continuous variable and using logistic regression with median hemoglobin level as the reference. Logistic regression was also performed with any incident decline in hemoglobin levels as the dependent variable.

resultsMetS was diagnosed in 263 (25%) participants. At baseline, MetS was associated with higher hemoglobin levels (B = 0.18, 95% confidence interval (CI) = 0.03-0.33, P = .02) and with hemoglobin levels above the median value (odds ratio (OR) = 1.65, 95% CI = 1.17-2.32, P = .004) after adjusting. After 6 years, MetS was associated with lower adjusted probability of lower hemoglobin levels (OR = 0.34, 95% CI = 0.15-0.79, P = .012) but only in the oldest tertile of participants.

conclusionMetS is associated with higher hemoglobin levels in older subjects and with lower probability of hemoglobin loss over 6 years in those in the oldest age group.

Indexed as

Frail ElderlyAgedAge FactorsAgingCross-Sectional StudiesFemaleFollow-Up StudiesGeriatric AssessmentHemoglobinsHumansItalyMaleMetabolic SyndromeOdds RatioPrevalenceProspective StudiesHemoglobins

Identifiers

PMID23647258
PMCPMC4154197
OpenAlexW2038825684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.