ReviewParasite immunology
The use of imaging to detect schistosomes and diagnose schistosomiasis.
Review in Parasite immunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Eggshell calcification of the urinary bladder in chronicRadiology case reports · 2026Article
- Feasibility of ultrasound radiomics based models for classification of liver fibrosis due to Schistosoma japonicum infection.PLoS neglected tropical diseases · 2024Article
- A 14-year follow-up of ultrasound-detected urinary tract pathology associated with urogenital schistosomiasis in women living in the Msambweni region of coastal Kenya.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2023Article
- The trend of schistosomiasis related bladder cancer in the lake zone, Tanzania: a retrospective review over 10 years period.Infectious agents and cancer · 2023Review
- Usefulness of ultrasound in sub-Saharan patients with a serological diagnosis of schistosomiasis.Infection · 2021Article
- Medical Imaging in the Diagnosis of Schistosomiasis: A Review.Pathogens (Basel, Switzerland) · 2021Review
- Intestinal FDG-PET/CT imaging of an Eritrean with schistosomiasis seen in Denmark.European journal of hybrid imaging · 2019Article
- Life cycle maintenance and drug-sensitivity assays for early drug discovery in Schistosoma mansoni.Nature protocols · 2019Article
- Live imaging of collagen deposition during experimental hepatic schistosomiasis and recovery: a view on a dynamic process.Laboratory investigation; a journal of technical methods and pathology · 2019Article
- Urinary schistosomiasis presented as bladder malignancy with pulmonary metastases: a case report.Annals of the Royal College of Surgeons of England · 2018Article
- Increasing prevalence of genitourinary schistosomiasis in Europe in the Migrant Era: Neglected no more?PLoS neglected tropical diseases · 2017Article
- In Vivo MRI Assessment of Hepatic and Splenic Disease in a Murine Model of Schistosomiasis [corrected].PLoS neglected tropical diseases · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Several imaging modalities have been employed to examine schistosomes and monitor schistosome-induced pathology. Ultrasound is a noninvasive imaging method that has long been used in the laboratory and in the field to evaluate pathological changes, notably fibrosis, that arise as a consequence of the host response to schistosome eggs lodging in a variety of tissues. Ultrasonography has been widely used to monitor changes in the extent of fibrosis and in spleen/liver enlargement following chemotherapeutic treatment for schistosomiasis. Imaging methods to monitor schistosomes themselves in vivo (as opposed to detecting schistosome-induced pathology) include positron emission tomography and fluorescence molecular tomography. Both approaches rely on schistosome uptake of tracers that are introduced into infected animals and that can be detected externally. These methods have been used to successfully detect schistosomes in vivo and to monitor their elimination following chemotherapeutic treatment. Direct monitoring of live schistosomes in vivo has been achieved using intravital microscopy, when the infected tissues of anaesthetized animals are exposed. Finally, schistosome eggs have been visualized by confocal laser scanning microscopy in infected mice as well as in a human patient with schistosomiasis hematobium. Further advances in imaging technologies seem likely to provide greater insight into disease progression and into the biology of schistosomes in the most relevant setting-within a live animal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.