Evidence map›Paper›PMID 23647057›Full record

ArticleAnalytical chemistry2013

An on-chip, multichannel droplet sorter using standing surface acoustic waves.

Sixing Li, Xiaoyun Ding, Feng Guo, Yuchao Chen, Michael Ian Lapsley, Sz-Chin Steven Lin, Lin Wang, J Philip McCoy, Craig E Cameron, Tony Jun Huang

Abstract read
In one paragraph

Article in Analytical chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Review
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  18. Single-Cell Microgels for Diagnostics and Therapeutics.Advanced functional materials · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sixing LiDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Xiaoyun Ding
Feng Guo
Yuchao Chen
Michael Ian Lapsley
Sz-Chin Steven Lin
Lin Wang
J Philip McCoy
Craig E Cameron
Tony Jun Huang

Funding

Flow Cytometry Core FacilityZICHL005905 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DAGUR, PRADEEP · 2009 to 2025
$32.3M
RNA DEPENDENT RNA POLYMERASE MECHANISMR01AI045818 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ARNOLD, JAMIE JON, CAMERON, CRAIG E. · 1999 to 2025
$7.5M
On-Chip Optofluidic Laser Scanning Confocal Microscope for Early Cancer DetectionDP2OD007209 · OD · PENNSYLVANIA STATE UNIVERSITY, THE · PI HUANG, TONY JUN · 2010 to 2010
$2.2M
NIAID NIH HHS AI45818NIH HHS 1DP2OD007209-01NIH HHS DP2 OD007209
6 · The paper itself

Abstract

The emerging field of droplet microfluidics requires effective on-chip handling and sorting of droplets. In this work, we demonstrate a microfluidic device that is capable of sorting picoliter water-in-oil droplets into multiple outputs using standing surface acoustic waves (SSAW). This device integrates a single-layer microfluidic channel with interdigital transducers (IDTs) to achieve on-chip droplet generation and sorting. Within the SSAW field, water-in-oil droplets experience an acoustic radiation force and are pushed toward the acoustic pressure node. As a result, by tuning the frequency of the SSAW excitation, the position of the pressure nodes can be changed and droplets can be sorted to different outlets at rates up to 222 droplets s(-1). With its advantages in simplicity, controllability, versatility, noninvasiveness, and capability to be integrated with other on-chip components such as droplet manipulation and optical detection units, the technique presented here could be valuable for the development of droplet-based micro total analysis systems (μTAS).

Indexed as

HydrodynamicsSoundEquipment DesignMicrofluidic Analytical TechniquesOilsSurface PropertiesWaterOilsWater

Identifiers

PMID23647057
PMCPMC3988909

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.