ArticleAsian Pacific journal of tropical biomedicine2013
In vitro effects of Salvia officinalis L. essential oil on Candida albicans.
Article in Asian Pacific journal of tropical biomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 78 citations in OpenAlex.
- Anti-inflammatory potential of an essential oil-containing mouthwash in elderly subjects enrolled in supportive periodontal therapy: a 6-week randomised controlled clinical trial.Clinical oral investigations · 2020Trial
- Chemical Composition and Multi-Target Bioactivity of Salvia sclarea L. Essential Oil From the Algerian Edough Massif: Antimicrobial, Enzyme-Inhibitory, and Molecular Docking Studies.Chemistry & biodiversity · 2026Article
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- The Potential ofPharmaceutics · 2025Article
- Balancing the Oral Redox State: Endogenous and Exogenous Sources of Reactive Oxygen Species and the Antioxidant Role of Lamiaceae and Asteraceae.Dentistry journal · 2025Review
- Antimicrobial efficacy and cytotoxicity of ethanolic extracts ofJournal of advanced periodontology & implant dentistry · 2025Article
- Exploring the therapeutic potential of medicinal plants and their active principles in dental care: A comprehensive review.Heliyon · 2024Review
- Article
- In vitro biological potential of the essential oil of some aromatic species used in Iranian traditional medicine.Inflammopharmacology · 2022Article
- Origanum vulgare L. essential oil inhibits virulence patterns of Candida spp. and potentiates the effects of fluconazole and nystatin in vitro.BMC complementary medicine and therapies · 2022Article
- Comparison of clinical indices and therapeutic effect of a mucoadhesive system containing Melissa 1% and triamcinolone 0.1% on lichenoid reactions.Dental research journal · 2022Article
- Chemical Constituents and Biologic Activities of Sage Species: A Comparison betweenAntioxidants (Basel, Switzerland) · 2020Article
- Essential Oils of Lamiaceae Family Plants as Antifungals.Biomolecules · 2020Review
- Effect of Clove and Thyme Essential Oils onMolecules (Basel, Switzerland) · 2019Article
- Evaluation of Preventive Antibacterial Properties of a Glass-Ionomer Cement Containing Purified Powder ofInternational journal of preventive medicine · 2019Article
- Characterization of Herbal Antifungal Agent,Contemporary clinical dentistry · 2018Article
- Antifungal Activity of Commercial Essential Oils and Biocides against Candida Albicans.Pathogens (Basel, Switzerland) · 2018Article
- Bioassay-Guided Isolation of Anti-Candida Biofilm Compounds From Methanol Extracts of the Aerial Parts ofFrontiers in pharmacology · 2018Article
- Early state research on antifungal natural products.Molecules (Basel, Switzerland) · 2014Review
- The comparison of antimicrobial effects of herbal and chemical agents on toothpaste: An experimental study.Dental research journalArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the anticandidal activities of Salvia officinalis L. (S. officinalis) essential oil against Candida albicans (C. albicans) and the inhibitory effects on the adhesion of C. albicans to polymethyl methacrylate (PMMA) resin surface.
methodsDisc diffusion method was first used to test the anticandidal activities of the S. officinalis L. essential oil against the reference strain (ATCC 90028) and 2 clinical strains of C. albicans. Then the minimal inhibitory concentration (MIC) and minimal lethal concentration (MLC) were determined by modified membrane method. The adhesion of C. albicans to PMMA resin surface was assessed after immersion with S. officinalis L. essential oil at various concentrations of 1×MIC, 0.5×MIC and 0.25×MIC at room temperature for 30 min. One-way ANOVA was used to compare the Candida cell adhesion with the pretreatment agents and Tukey's test was used for multiple comparisons.
resultsS. officinalis L. essential oil exhibited anticandidal activity against all strains of C. albicans with inhibition zone ranging from 40.5 mm to 19.5 mm. The MIC and MLC of the oil were determined as 2.780 g/L against all test strains. According to the effects on C. albicans adhesion to PMMA resin surface, it was found that immersion in the essential oil at concentrations of 1×MIC (2.780 g/L), 0.5×MIC (1.390 g/L) and 0.25×MIC (0.695 g/L) for 30 min significantly reduced the adhesion of all 3 test strains to PMMA resin surface in a dose dependent manner (P<0.05).
conclusionsS. officinalis L. essential oil exhibited anticandidal activities against C. albicans and had inhibitory effects on the adhesion of the cells to PMMA resin surface. With further testing and development, S. officinalis essential oil may be used as an antifungal denture cleanser to prevent candidal adhesion and thus reduce the risk of candida-associated denture stomatitis.
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