Evidence map›Paper›PMID 23646208›Full record

ArticleThe Pan African medical journal2013

Chromatographic immunoassays for Helicobacter pylori detection--are they reliable in Mali, West Africa?

Ingvild Austarheim, Kari Tvete Inngjerdingen, Berit Smestad Paulsen, Adiaratou Togola, Chiaka Diakité, Drissa Diallo

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. BioMed research international · 2019
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ingvild AustarheimSchool of Pharmacy, University of Oslo, P.O. Box 1068 Blindern, 0316 Oslo, Norway.
Kari Tvete Inngjerdingen
Berit Smestad Paulsen
Adiaratou Togola
Chiaka Diakité
Drissa Diallo
University of Oslo · NOMali-Folkecenter · ML

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGastrointestinal diseases are major reasons for morbidity in Mali. As Helicobacter pylori is known to play a major role in gastritis and gastric ulcer we wanted to find a simple method for detection.

methodsTwenty-nine volunteers with confirmed gastric ulcer by gastroscopy and 59 randomly selected volunteers were diagnosed by using the rapid serological test Clearview(®) H. Pylori. The ImmunoCard STAT!(®) HpSA(®)test was applied on stool from 65 volunteers seeking help for gastrointestinal related ailments.

resultsA Helicobacter pylori prevalence of 21% was found among the individuals with confirmed gastric ulcer, 44% among the randomly selected volunteers and 14% in individuals with gastrointestinal related ailments.

conclusionAccording to what is already known about the aetiology of gastric ailments and the prevalence of Helicobacter pylori in neighboring countries, the infection rates in our study appear strikingly low. This might indicate that Clearview(®) H. Pylori and ImmunoCard STAT!(®) HpSA(®) have low sensitivities in the populations studied. Strain variability of H. pylori may be an explanation. The tests need to be properly evaluated in Mali before they can be relied upon as diagnostic tools.

Indexed as

Chromatography, AffinityAdultAgedFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMaliMiddle AgedReproducibility of ResultsHelicobacter pylorirapid testsserological testStool test

Identifiers

PMID23646208
PMCPMC3641924
OpenAlexW2063154885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.