Evidence map›Paper›PMID 23646068›Full record

ArticleCellular and molecular bioengineering2013

Cytoplasmic dynein: tension generation on microtubules and the nucleus.

Nandini Shekhar, Jun Wu, Richard B Dickinson, Tanmay P Lele

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular bioengineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nandini ShekharDepartment of Chemical Engineering, University of Florida, Gainesville, FL 32611.
Jun Wu
Richard B Dickinson
Tanmay P Lele
University of Florida · US

Funding

SUBSTRATE RIGIDITY AND GENE EXPRESSION: Role of Nuclear TensionR01EB014869 · NIBIB · UNIVERSITY OF FLORIDA · PI LELE, TANMAY P. · 2012 to 2019
$3.4M
Cytoskeletal force generation on the nucleusR01GM102486 · NIGMS · UNIVERSITY OF FLORIDA · PI LELE, TANMAY P. · 2012 to 2015
$1.2M
NIBIB NIH HHS R01 EB014869NIGMS NIH HHS R01 GM102486
6 · The paper itself

Abstract

Cytoplasmic dynein is a microtubule dependent motor protein that is central to vesicle transport, cell division and organelle positioning. Recent studies suggest that dynein can generate significant pulling forces on intracellular structures as it motors along microtubules. In this review, we discuss how dynein-generated pulling forces position the nucleus and the centrosome.

Indexed as

Centrosome CenteringCytoplasmic DyneinForce GenerationNuclear Positioning

Identifiers

PMID23646068
PMCPMC3640586
OpenAlexW2061445529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.