Evidence map›Paper›PMID 23646067›Full record

ArticleCellular and molecular bioengineering2011

Regulation of Adipose Tissue Metabolism in Humans: Analysis of Responses to the Hyperinsulinemic-Euglycemic Clamp Experiment.

Jaeyeon Kim, Gerald M Saidel, Satish C Kalhan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular bioengineering, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jaeyeon KimDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA ; Center for Modeling Integrated Metabolic Systems, Case Western Reserve University, Cleveland, OH 44106, USA ; Department of Pathobiology, Lerner Research Institute, NE4-203, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Gerald M Saidel
Satish C Kalhan
Case Western Reserve University · USCleveland Clinic Lerner College of Medicine · US

Funding

CORE--SYSTEM MODELING INTEGRATIONP50GM066309 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI SAIDEL, GERALD M · 2002 to 2006
$11.4M
Sulfur Amino Acid Metabolism in NAFLDR01DK079937 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI KALHAN, SATISH C · 2009 to 2010
$1.1M
NIDDK NIH HHS R01 DK079937NIGMS NIH HHS P50 GM066309
6 · The paper itself

Abstract

The suppression of lipolysis is one of the key metabolic responses of the adipose tissue during hyperinsulinemia. The failure to respond and resulting increase in plasma fatty acids could contribute to the development of insulin resistance and perturbations in the fuel homeostasis in the whole body. In this study, a mechanistic, computational model of adipose tissue metabolism

Indexed as

InsulinLipolysisMathematical modelRe-esterificationTG-FA cycle

Identifiers

PMID23646067
PMCPMC3641796
OpenAlexW2066605810

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.