Evidence map›Paper›PMID 23646063›Full record

ArticleSoft matter2012

Low intensity ultrasound perturbs cytoskeleton dynamics.

Natalya Mizrahi, Enhua H Zhou, Guillaume Lenormand, Ramaswamy Krishnan, Daphne Weihs, James P Butler, David A Weitz, Jeffrey J Fredberg, Eitan Kimmel

Open access · greenAbstract read
In one paragraph

Article in Soft matter, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 90 citations in OpenAlex.

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  7. Start your engines: How migratory fibroblasts respond to and remember mechanical stretch.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  18. IEEE access : practical innovations, open solutions · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Natalya MizrahiFaculty of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa, Israel ; Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, Massachusetts, USA.
Enhua H Zhou
Guillaume Lenormand
Ramaswamy Krishnan
Daphne Weihs
James P Butler
David A Weitz
Jeffrey J Fredberg
Eitan Kimmel
Harvard University · USTechnion – Israel Institute of Technology · ILBeth Israel Deaconess Medical Center · US

Funding

Micromechanics of the airway smooth muscle cellR01HL065960 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI FREDBERG, JEFFREY J · 2000 to 2009
$6.3M
The resident cell in the asthmatic airway: A victim of its physical microenvironR01HL102373 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI FREDBERG, JEFFREY J, TSCHUMPERLIN, DANIEL J. · 2011 to 2014
$1.9M
NHLBI NIH HHS R01 HL065960NHLBI NIH HHS R01 HL102373
6 · The paper itself

Abstract

Therapeutic ultrasound is widely employed in clinical applications but its mechanism of action remains unclear. Here we report prompt fluidization of a cell and dramatic acceleration of its remodeling dynamics when exposed to low intensity ultrasound. These physical changes are caused by very small strains (10

Identifiers

PMID23646063
PMCPMC3641826
OpenAlexW2056360581

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.