Evidence map›Paper›PMID 23645942›Full record

ArticleAnnals of statistics2012

MULTIVARIATE VARYING COEFFICIENT MODEL FOR FUNCTIONAL RESPONSES.

Hongtu Zhu, Runze Li, Linglong Kong

Abstract read
In one paragraph

Article in Annals of statistics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Competing Risk Modeling with Bivariate Varying Coefficients to Understand the Dynamic Impact of COVID-19.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Surface Functional Models.Journal of multivariate analysis · 2020
    Article
  16. Article
  17. Fast Covariance Estimation for Multivariate Sparse Functional Data.Stat (International Statistical Institute) · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hongtu ZhuDepartments of Biostatistics and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Runze Li
Linglong Kong

Funding

UNC CLINICAL AND TRANSLATIONAL SCIENCE AWARD: BPCAUL1RR025747 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$44.6M
Washington University ConsoritumU54EB005149 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON · 2004 to 2013
$39.3M
THE REFINEMENT &APPLICATION OF MEDICAL DECISION MAKING IN PREVENTION SCIENCESP50DA010075 · NIDA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI LANZA, STEPHANIE T · 1996 to 2014
$24.5M
Statistical Methods for Cancer Clinical TrialsP01CA142538 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIN, DANYU · 2010 to 2019
$21.3M
UNC Clinical Translation Science Award-K12 Scholars Program (KL2)KL2RR025746 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$9.0M
Statistical Analysis of Biomedical Imaging Data in Curved SpaceR01MH086633 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI IBRAHIM, JOSEPH G · 2010 to 2018
$2.9M
New Statistical Models for Intensive Longitudinal DataR21DA024260 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI DIERKER, LISA C, LI, RUNZE · 2007 to 2010
$1.2M
UNC Clinical Translation Science Award-T32 Program (TL1)TL1RR025745 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$678k
Longitudinal Analysis of Biomedical Imaging DataR21AG033387 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZHU, HONGTU · 2009 to 2010
$334k
NCI NIH HHS P01 CA142538NCRR NIH HHS KL2 RR025746NCRR NIH HHS TL1 RR025745NCRR NIH HHS UL1 RR025747NIA NIH HHS R21 AG033387NIBIB NIH HHS U54 EB005149NIDA NIH HHS P50 DA010075NIDA NIH HHS R21 DA024260NIMH NIH HHS R01 MH086633
6 · The paper itself

Abstract

Motivated by recent work studying massive imaging data in the neuroimaging literature, we propose multivariate varying coefficient models (MVCM) for modeling the relation between multiple functional responses and a set of covariates. We develop several statistical inference procedures for MVCM and systematically study their theoretical properties. We first establish the weak convergence of the local linear estimate of coefficient functions, as well as its asymptotic bias and variance, and then we derive asymptotic bias and mean integrated squared error of smoothed individual functions and their uniform convergence rate. We establish the uniform convergence rate of the estimated covariance function of the individual functions and its associated eigenvalue and eigenfunctions. We propose a global test for linear hypotheses of varying coefficient functions, and derive its asymptotic distribution under the null hypothesis. We also propose a simultaneous confidence band for each individual effect curve. We conduct Monte Carlo simulation to examine the finite-sample performance of the proposed procedures. We apply MVCM to investigate the development of white matter diffusivities along the genu tract of the corpus callosum in a clinical study of neurodevelopment.

Indexed as

Functional responseGlobal test statisticMultivariate varying coefficient modelSimultaneous confidence bandWeak convergence

Identifiers

PMID23645942
PMCPMC3641708

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.