ArticleEuropean journal of epidemiology2013
Hazardous alcohol consumption is associated with increased levels of B-type natriuretic peptide: evidence from two population-based studies.
Article in European journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Alcohol consumption and the risk of heart failure: the Suita Study and meta-analysis of prospective cohort studies.Environmental health and preventive medicine · 2023Pooled it
- Impact of Modifiable Risk Factors on B-type Natriuretic Peptide and Cardiac Troponin T Concentrations.The American journal of cardiology · 2016Trial
- Association Between Serum N-Terminal Prohormone of Brain Natriuretic Peptide (NT-proBNP) Levels and Frailty in Community-Dwelling Old-Old Older Adults - SONIC Study.Circulation reports · 2025Article
- Preventable mortality in the Russian Federation: a retrospective, regional level study.The Lancet regional health. Europe · 2023Article
- Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function.Open heart · 2021Article
- Why does Russia have such high cardiovascular mortality rates? Comparisons of blood-based biomarkers with Norway implicate non-ischaemic cardiac damage.Journal of epidemiology and community health · 2020Article
- Sustained heavy drinking over 25 years is associated with increased N-terminal-pro-B-type natriuretic peptides in early old age: Population-based cohort study.Drug and alcohol dependence · 2020Observational
- Article
- Evidence for a Direct Harmful Effect of Alcohol on Myocardial Health: A Large Cross-Sectional Study of Consumption Patterns and Cardiovascular Disease Risk Biomarkers From Northwest Russia, 2015 to 2017.Journal of the American Heart Association · 2020Article
- Article
- Know Your Heart: Rationale, design and conduct of a cross-sectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 35-69 years from two Russian cities, 2015-18.Wellcome open research · 2018Article
- High cardiovascular mortality in Russia: role of alcohol versus smoking, blood pressure, and treatment.Nature reviews. Cardiology · 2015Article
- Maternal obesity during pregnancy and cardiovascular development and disease in the offspring.European journal of epidemiology · 2015Review
- The Rotterdam Study: 2016 objectives and design update.European journal of epidemiology · 2015Article
- Sex Differences in Biological Markers of Health in the Study of Stress, Aging and Health in Russia.PloS one · 2015Article
- Self-reported symptoms of chronic cough and breathlessness in working-age men in the city of Izhevsk, Russia: associations with cardiovascular disease risk factors and comorbidities.BMJ open respiratory research · 2015Article
- Alcohol consumption and risk of incident heart failure in older men: a prospective cohort study.Open heartArticle
Corrections and comments
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Authors and funding
15 authors at 9 institutions in 3 countries.
Funding
Abstract
Russia has very high mortality from cardiovascular disease (CVD), with evidence that heavy drinking may play a role. To throw further light on this association we have studied the association of alcohol with predictors of CVD risk including B-type natriuretic peptide (BNP). Levels of BNP increase primarily in response to abnormal cardiac chamber wall stretch which can occur both as a result of atherosclerosis as well as due to other types of damage to the myocardium. No previous population-based studies have investigated the association with alcohol. We analysed cross-sectional data on drinking behaviour in 993 men aged 25-60 years from the Izhevsk Family Study 2 (IFS2), conducted in the Russian city of Izhevsk in 2008-2009. Relative to non-drinkers, men who drank hazardously had an odds ratio (OR) of being in the top 20 % of the BNP distribution of 4.66 (95 % CI 2.13, 10.19) adjusted for age, obesity, waist-hip ratio, and smoking. Further adjustment for class of hypertension resulted in only slight attenuation of the effect, suggesting that this effect was not secondary to the influence of alcohol on blood pressure. In contrast hazardous drinking was associated with markedly raised ApoA1 and HDL cholesterol levels, but had little impact on levels of ApoB and LDL cholesterol. Similar but less pronounced associations were found in the Belfast (UK) component of the PRIME study conducted in 1991. These findings suggest that the association of heavy drinking with increased risk of cardiovascular disease may be partly due to alcohol-induced non-atherosclerotic damage to the myocardium.
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