ArticleTransgenic research2013
GmTMT2a from soybean elevates the α-tocopherol content in corn and Arabidopsis.
Article in Transgenic research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Survey of tocopherol and the associated genetic loci in wheat grain.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Vitamin E in Plants: Biosynthesis Pathways, Biofortification Strategies, and Regulatory Dynamics.International journal of molecular sciences · 2025Review
- Variation in the Content and Composition of Tocols in a Wheat Population.Foods (Basel, Switzerland) · 2022Article
- Assessment of Biofortification Approaches Used to Improve Micronutrient-Dense Plants That Are a Sustainable Solution to Combat Hidden Hunger.Journal of soil science and plant nutrition · 2022Review
- Genome-wide association studies reveal novel QTLs, QTL-by-environment interactions and their candidate genes for tocopherol content in soybean seed.Frontiers in plant science · 2022Article
- Vitamins in Cereals: A Critical Review of Content, Health Effects, Processing Losses, Bioaccessibility, Fortification, and Biofortification Strategies for Their Improvement.Frontiers in nutrition · 2021Review
- Over-expression of a γ-tocopherol methyltransferase gene in vitamin E pathway confers PEG-simulated drought tolerance in alfalfa.BMC plant biology · 2020Article
- Overexpression of the maize γ-tocopherol methyltransferase gene (ZmTMT) increases α-tocopherol content in transgenic Arabidopsis and maize seeds.Transgenic research · 2020Article
- Identification of quantitative trait loci for increased α-tocopherol biosynthesis in wild soybean using a high-density genetic map.BMC plant biology · 2019Article
- FromFrontiers in plant science · 2018Review
- Evaluation of Biosynthesis, Accumulation and Antioxidant Activityof Vitamin E in Sweet Corn (Zea mays L.) during Kernel Development.International journal of molecular sciences · 2017Article
- Natural diversity of seed α-tocopherol ratio in wild soybean (Breeding science · 2016Article
- Natural variations in OsγTMT contribute to diversity of the α-tocopherol content in rice.Molecular genetics and genomics : MGG · 2015Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tocochromanol, or vitamin E, plays a crucial role in human and animal nutrition and is synthesized only by photosynthetic organisms. γ-Tocopherol methyltransferase (γ-TMT), one of the key enzymes in the tocopherol biosynthetic pathway in plants, converts γ, δ-tocopherols into α-, β-tocopherols. Tocopherol content was investigated in 15 soybean cultivars and GmTMT2 was isolated from five varieties based on tocopherol content. GmTMT2a was expressed in E. coli and the purified protein effectively converted γ-tocopherol into α-tocopherol in vitro. Overexpression of GmTMT2a enhanced α-tocopherol content 4-6-fold in transgenic Arabidopsis, and α-tocopherol content increased 3-4.5-fold in transgenic maize seed, which correlated with the accumulation of GmTMT2a. Transgenic corn that is α-tocopherol-rich may be beneficial for animal health and growth.
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