ArticleJournal of Zhejiang University. Science. B2013
Long-term comparison of full-bed deep anterior lamellar keratoplasty and penetrating keratoplasty in treating keratoconus.
Article in Journal of Zhejiang University. Science. B, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Graft survival rate of deep anterior lamellar keratoplasty for keratoconus: A meta-analysis.Medicine · 2018Pooled it
- Efficacy and safety of deep anterior lamellar keratoplasty vs. penetrating keratoplasty for keratoconus: a meta-analysis.PloS one · 2015Pooled it
- Long-Term Graft Survival and Visual Outcomes in Deep Anterior Lamellar Keratoplasty (DALK): A Narrative Review.Journal of ophthalmology · 2026Review
- Assessing Access to and Utilization of the Advanced Diagnostic and Management Equipment for Early Keratoconus in Public and Private Healthcare Facilities Across Nyanza and Western Kenya.Clinical optometry · 2025Article
- Risk Factors for Glaucoma and Ocular Hypertension and Post-Transplant Complications in Keratoconus: A Multivariable Analysis.Journal of clinical medicine · 2024Article
- Mechanism and treatment of secondary glaucoma after corneal transplantation: a review.Frontiers in ophthalmology · 2024Review
- Long-term outcomes of deep anterior lamellar versus penetrating keratoplasty for keratoconus.The British journal of ophthalmology · 2023Article
- Management of keratoconus: an updated review.Frontiers in medicine · 2023Review
- Complications in deep anterior lamellar keratoplasty - A retrospective interventional analysis in a large series.Indian journal of ophthalmology · 2022Article
- Surgical management of glaucoma following different keratoplasty techniques.International ophthalmology · 2022Article
- Current Perspectives on Corneal Transplantation.Clinical ophthalmology (Auckland, N.Z.) · 2022Review
- Donor and Recipient Sex Matching and Corneal Graft Failure in High-Risk and Non-High-Risk Patients.Journal of ophthalmology · 2022Article
- Corneal Refractive Surgery in Patients with a History of Herpes Simplex Keratitis: A Narrative Review.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
- Small-Incision Femtosecond Laser-Assisted Intracorneal Concave Lenticule Implantation in Patients With Keratoconus.Cornea · 2019Article
- Comparison of clinical outcomes of deep anterior lamellar keratoplasty and excimer laser assisted anterior lamellar keratoplasty in keratoconus.International journal of ophthalmology · 2019Article
- Deep anterior lamellar keratoplasty: A surgeon's guide.Journal of current ophthalmology · 2018Review
- Gender differences in keratoconus keratoplasty: a 25-year study in Southern Brazil and global perspective.International ophthalmology · 2018Article
- Updates on Managements for Keratoconus.Journal of current ophthalmology · 2018Review
- Comparison of outcomes and complications of deep anterior lamellar keratoplasty and penetrating keratoplasty performed in a large group of patients with keratoconus.International ophthalmology · 2018Article
- Etiology and failure analysis of anterior lamellar keratoplasty.International journal of ophthalmology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare postoperative outcomes of full-bed deep anterior lamellar keratoplasty (DALK) with penetrating keratoplasty (PK) in treating keratoconus.
methodsSeventy-five eyes of 64 patients who received full-bed DALK and 52 eyes of 51 patients who received PK between June 2000 and August 2010 were included in this retrospective study. Full-bed DALK was performed using Yao's hooking-detaching technique. PK was performed using a standard technique. Intraoperative and postoperative complications, visual acuity, rejection, graft survival, endothelial cell density, corneal sensation recovery, and re-innervation were compared between the two groups.
resultsA best correct visual acuity of 0.5 or better was achieved in 90.7% of eyes after full-bed DALK and in 92.3% of eyes after PK (P=0.75). By the fifth postoperative year, graft endothelial cell loss reached 34.6% in the PK group vs. 13.9% in the full-bed DALK group (P<0.001). There were no statistical differences in corneal sensitivity recovery or corneal re-innervation between the groups (P>0.05). Intraoperative microperforation occurred in seven out of 75 (9.3%) eyes with a temporally postoperative double anterior chamber in two eyes in the full-bed DALK group. Postoperative complications in the PK vs. the full-bed DALK groups respectively were: rejection (7.7% vs. 0%, P=0.015), high intraocular pressure (IOP) (46.2% vs. 1.3%, P<0.001), secondary glaucoma (9.6% vs. 0%, P=0.006), complicated cataract (19.2% vs. 0%, P<0.001), and wound dehiscence (9.6% vs. 0%, P=0.006).
conclusionsBoth full-bed DALK and PK can offer long-term satisfactory visual outcomes for keratoconus. Graft rejection, secondary glaucoma, complicated cataracts, and constant endothelial cell loss were observed in eyes only after PK.
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Registered trials
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