ArticleAsian journal of andrology2013
Impact of the association between elevated oestradiol and low testosterone levels on erectile dysfunction severity.
Article in Asian journal of andrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- A Review on Testosterone: Estradiol Ratio-Does It Matter, How Do You Measure It, and Can You Optimize It?The world journal of men's health · 2025Review
- Hormones, Age, and Erectile Dysfunction: Should Routine Testing Be Part of the Initial Evaluation?Diagnostics (Basel, Switzerland) · 2025Article
- Factors Associated With Erectile Dysfunction in Men: A Cross-Sectional Study From Balochistan, Pakistan.Cureus · 2025Article
- Article
- Associations of waist circumference with sex steroid hormones among 4031 USA children and adolescents.Asian journal of andrology · 2023Article
- Erectile dysfunction as a marker of endocrine and glycemic disorders.Journal of endocrinological investigation · 2022Article
- Role of testosterone to estradiol ratio in predicting the efficacy of recombinant human chorionic gonadotropin and testosterone treatment in male hypogonadism.Archives of endocrinology and metabolism · 2021Article
- Estradiol-Testosterone Imbalance Is Associated with Erectile Dysfunction in Patients with Klinefelter Syndrome.Journal of clinical medicine · 2021Article
- Effect of estradiol on penile erection: a cross-sectional study.Translational andrology and urology · 2019Article
- The relationship between hydration status, male sexual dysfunction and depression in hemodialysis patients.Therapeutics and clinical risk management · 2018Article
- Psychobiological Protective Factors Modifying the Association Between Age and Sexual Health in Men: Findings From the Men's Health 40+ Study.American journal of men's health · 2017Article
- Association of Urinary Phthalate Metabolites With Erectile Dysfunction in Racial and Ethnic Groups in the National Health and Nutrition Examination Survey 2001-2004.American journal of men's health · 2017Article
- Endocrine evaluation of erectile dysfunction.Endocrine · 2014Review
- Estradiol is an independent risk factor for organic erectile dysfunction in eugonadal young men.Asian journal of andrologyArticle
- The role of estradiol in male reproductive function.Asian journal of andrologyReview
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our aim was to assess the impact of the association between elevated oestradiol (E2) and low testosterone (T) levels on erectile dysfunction (ED) severity. A total of 614 male patients with ED and a normal or low T level in association with normal or elevated E2 levels were enrolled. Patients underwent routine laboratory investigations in addition to measurements of total T, total E2, follicle-stimulating hormone (FSH), luteinizing hormone (LH) and prolactin. We compared the responses to the erectile function domain, Q3 (achieving erection) and Q4 (maintaining erection) of the International Index for Erectile Function (IIEF) score in patients with the following: normal T and E2 levels; low T level; low T level and elevated E2 level; and elevated E2 level. Of the patients included, 449 (73.1%) had normal T and E2 levels, 110 (17.9%) had a low T level, 36 (5.9%) had a low T level and an elevated E2 level, and 19 (3.1%) had an elevated E2 level. Increased ED severity was significantly associated with low T levels, elevated E2 levels, and both a low T level and an elevated E2 level. Additionally, the mean values of the EF-domain, Q3 and Q4 were significantly lower in patients with both a low T level and an elevated E2 level compared to patients with any condition alone. In conclusion, a low T level had the primary effect on erectile function; however, a concomitantly elevated E2 level had an additive impairment effect.
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