Trial reportClinics (Sao Paulo, Brazil)2013
Objective evaluation of plantar hyperhidrosis after sympathectomy.
Trial report in Clinics (Sao Paulo, Brazil), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Randomized trial - oxybutynin for treatment of persistent plantar hyperhidrosis in women after sympathectomy.Clinics (Sao Paulo, Brazil) · 2014Trial
- The use of an objective method (continuous exosomatic electrodermal activity without external stimuli) to evaluate patients with hyperhidrosis undergoing video-assisted sympathectomy.Einstein (Sao Paulo, Brazil) · 2026Article
- Quality of life and compensatory hyperhidrosis following thoracoscopic sympathectomy: a retrospective cohort study.Journal of cardiothoracic surgery · 2025Article
- Endoscopic thoracic sympathotomy for primary hyperhidrosis: predictors of outcome over a 10-year period.Surgical endoscopy · 2022Article
- Effects of lower thoracic sympathicotomy on plantar hyperhidrosis.Journal of thoracic disease · 2021Article
- Symptoms of anxiety and depression in patients with primary hyperhidrosis and its association with the result of clinical treatment with oxybutynin.Clinics (Sao Paulo, Brazil)Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
objectiveThe aim of the present study was to prospectively, randomly, blindly, and objectively investigate how surgery affects plantar sudoresis in patients with palmar and plantar hyperhidrosis over a one-year period using a sudorometer (VapoMeter).
methodsFrom February 2007 to May 2009, 40 consecutive patients with combined palmar hyperhidrosis and plantar hyperhidrosis underwent video-assisted thoracic sympathectomy at the T3 or T4 ganglion level (15 women and 25 men, with a mean age of 25 years).
resultsImmediately after the operation and during the one-year follow-up, all of the patients were free from palmar hyperhidrosis episodes. Compensatory hyperhidrosis of varying degrees was observed in 35 (87.5%) patients after one year. Only two (2.5%) patients suffered from severe compensatory hyperhidrosis. There was a large initial improvement in plantar hyperhidrosis in 46.25% of the cases, followed by a progressive regression of that improvement, such that only 30% continued to show this improvement after one year. The proportion of patients whose condition worsened increased progressively (from 21.25% to 47.50%), and the proportion of stable patients decreased (32.5% to 22.50%). This was not related to resection level; however, a lower intensity of plantar hyperhidrosis prior to sympathectomy correlated with worse evolution.
conclusionPatients with palmar hyperhidrosis and plantar hyperhidrosis who underwent video-assisted thoracic sympathectomy to treat their palmar hyperhidrosis exhibited good initial improvement in plantar hyperhidrosis, which then decreased to lesser degrees of improvement over a one-year period following the surgery. For this reason, video-assisted thoracic sympathectomy should not be performed when only plantar hyperhidrosis is present.
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