ArticleNature structural & molecular biology2013
CENP-A confers a reduction in height on octameric nucleosomes.
Article in Nature structural & molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 46 citations in OpenAlex.
- CENP-A in cancer: from centromere identity to genome instability.Molecular biology reports · 2026Review
- The dynamic centromere.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025Review
- Centromere structure and function: lessons from Drosophila.Genetics · 2023Article
- Review
- Asymmetric Centromeres Differentially Coordinate with Mitotic Machinery to Ensure Biased Sister Chromatid Segregation in Germline Stem Cells.Cell stem cell · 2019Article
- The regulation of chromosome segregation via centromere loops.Critical reviews in biochemistry and molecular biology · 2019Review
- Breaking Symmetry - Asymmetric Histone Inheritance in Stem Cells.Trends in cell biology · 2017Review
- Chromatin dynamics during the cell cycle at centromeres.Nature reviews. Genetics · 2017Review
- The supercoiling state of DNA determines the handedness of both H3 and CENP-A nucleosomes.Nanoscale · 2017Article
- A Molecular View of Kinetochore Assembly and Function.Biology · 2017Review
- Chromatin assembly: Journey to the CENter of the chromosome.The Journal of cell biology · 2016Review
- Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.Molecular cell · 2016Review
- Article
- A Study into the Collision-induced Dissociation (CID) Behavior of Cross-Linked Peptides.Molecular & cellular proteomics : MCP · 2016Article
- Article
- Shearing of the CENP-A dimerization interface mediates plasticity in the octameric centromeric nucleosome.Scientific reports · 2015Article
- The right place at the right time: chaperoning core histone variants.EMBO reports · 2015Review
- Review
- A cell-free CENP-A assembly system defines the chromatin requirements for centromere maintenance.The Journal of cell biology · 2015Article
- Structural transitions of centromeric chromatin regulate the cell cycle-dependent recruitment of CENP-N.Genes & development · 2015Article
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
Nucleosomes with histone H3 replaced by CENP-A direct kinetochore assembly. CENP-A nucleosomes from human and Drosophila have been reported to have reduced heights as compared to canonical octameric H3 nucleosomes, thus suggesting a unique tetrameric hemisomal composition. We demonstrate that octameric CENP-A nucleosomes assembled in vitro exhibit reduced heights, indicating that they are physically distinct from H3 nucleosomes and negating the need to invoke the presence of hemisomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.