Evidence map›Paper›PMID 23642182›Full record

ReviewWorld journal of surgical oncology2013

Lymphoepithelioma-like hepatocellular carcinoma: a case report and a review of the literature.

Masahiro Shinoda, Yoshie Kadota, Hanako Tsujikawa, Yohei Masugi, Osamu Itano, Akihisa Ueno, Kisho Mihara, Taizo Hibi, Yuta Abe, Hiroshi Yagi and 6 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in World journal of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

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  10. A case of small well-differentiated hepatocellular carcinoma with marked lymphocytic infiltrate.International journal of clinical and experimental pathology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Masahiro ShinodaDepartment of Surgery, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan. masa02114@yahoo.co.jp
Yoshie Kadota
Hanako Tsujikawa
Yohei Masugi
Osamu Itano
Akihisa Ueno
Kisho Mihara
Taizo Hibi
Yuta Abe
Hiroshi Yagi
Minoru Kitago
Shigeyuki Kawachi
Akihiro Tanimoto
Michiie Sakamoto
Minoru Tanabe
Yuko Kitagawa
Keio University · JPKeio University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a rare case of lymphoepithelioma-like hepatocellular carcinoma. A 79-year-old Japanese man had undergone curative resection of extrahepatic bile ducts because of bile duct cancer 9 years prior. The bile duct cancer was diagnosed as mucosal adenocarcinoma, and the patient had been followed up every 6 months for the last 9 years. A recent computed tomography examination revealed a tumor, 4.2 cm in size, in the lateral segment of the liver. Based on the imaging findings, the tumor was diagnosed as hepatocellular carcinoma. Serology tests were negative for hepatitis B and C viruses. Chest and abdominal image analyses showed no evidence of metastasis, but a swollen lymph node was noted around the abdominal aorta. The patient subsequently underwent extended lateral segmentectomy and resection of the swollen lymph node. Microscopically, the tumor had the characteristic appearance of poorly differentiated hepatocellular carcinoma. Moreover, an abundant infiltration of inflammatory cells was observed in the tumor. Therefore, we diagnosed the tumor as lymphoepithelioma-like hepatocellular carcinoma. The resected para-aortic lymph node also had a carcinoma with features similar to those of the main tumor. The patient has been alive for 20 months since performance of the surgery. Since the first report of lymphoepithelioma-like hepatocellular carcinoma in 2000, only nine cases have been reported in the medical literature, and the clinicopathological features of the disease have not been well documented. Herein, we describe the clinicopathological features of this case for further understanding of the disease and review past cases in the literature.

Indexed as

AdenocarcinomaAgedBile Duct NeoplasmsCarcinoma, HepatocellularDiagnosis, DifferentialHumansLiver NeoplasmsLymphatic MetastasisLymphocytes, Tumor-InfiltratingMalePrognosisReview Literature as TopicTomography, X-Ray Computed

Identifiers

PMID23642182
PMCPMC3654885
OpenAlexW2125673820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.