ArticleInternational journal for parasitology. Drugs and drug resistance2013
Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis.
Article in International journal for parasitology. Drugs and drug resistance, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 71 citations in OpenAlex.
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- The induced and intrinsic resistance ofMicrobiology spectrum · 2024Article
- Natural Perylenequinone Compounds as Potent Inhibitors ofLife (Basel, Switzerland) · 2023Article
- Plumbagin: A Promising In Vivo Antiparasitic Candidate againstBiomedicines · 2023Article
- Molluscicidal and Larvicidal Potency ofPharmaceutics · 2023Article
- In vitro and in silico scolicidal effect of sanguinarine on the hydatid cyst protoscoleces.PloS one · 2023Article
- Antischistosomal effects ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Qualitative and Quantitative Analysis of Secondary Metabolites in Morphological Parts of Paulownia Clon In Vitro 112Molecules (Basel, Switzerland) · 2022Article
- Alkaloids in Contemporary Drug Discovery to Meet Global Disease Needs.Molecules (Basel, Switzerland) · 2021Review
- Ginger (Zingiber Officinale)-derived nanoparticles in Schistosoma mansoni infected mice: Hepatoprotective and enhancer of etiological treatment.PLoS neglected tropical diseases · 2021Article
- Influence of different elicitors on BIA production in Macleaya cordata.Scientific reports · 2021Article
- Modulation of benzylisoquinoline alkaloid biosynthesis by overexpression berberine bridge enzyme in Macleaya cordata.Scientific reports · 2018Article
- Hairy root induction and benzylisoquinoline alkaloid production in Macleaya cordata.Scientific reports · 2018Article
- The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases.Molecules (Basel, Switzerland) · 2016Review
- Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms.Scientific reports · 2016Article
- Sanguinaria canadensis: Traditional Medicine, Phytochemical Composition, Biological Activities and Current Uses.International journal of molecular sciences · 2016Review
- Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris.PLoS neglected tropical diseases · 2016Article
- Natural products as leads in schistosome drug discovery.Molecules (Basel, Switzerland) · 2015Article
- Phytochemical profile ofPhytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2015Review
- Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni.PLoS neglected tropical diseases · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Schistosomiasis, a snail-borne parasitic disease, affects more than 200 million people worldwide. Currently the treatment of schistosomiasis relies on a single therapy of praziquantel, a drug developed over 30 years ago. Thus, there is an urgent need to develop alternative antischistosomal drugs. In the pursuit of novel antischistosomal drugs, we examined the antischistosomal activities of 45 compounds that had been reported to exhibit antimicrobial and/or antiparasitic activities. Two plant-derived compounds, plumbagin and sanguinarine, were found to possess potent antischistosomal activities
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.