ArticleTherapeutic advances in musculoskeletal disease2013
Dual-energy X-ray absorptiometry versus quantitative ultrasonography in diagnosing osteoporosis in patients with refractory epilepsy and chronic antiepileptic drug use.
Article in Therapeutic advances in musculoskeletal disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 18 citations in OpenAlex.
- QUS characteristics in Normal Population: a Mini Review and our experience.Journal of diabetes and metabolic disorders · 2022Article
- Effects of new antiseizure medication on bone metabolism and bone mineral density in children: A meta-analysis.Frontiers in pediatrics · 2022Article
- Association of Heel Bone Mineral Density With Incident Disability and Mortality in Community-Dwelling Older Adults.JBMR plus · 2020Article
- A call to action for osteoporosis research in sub-saharan Africa.Ghana medical journal · 2020Review
- Prevalence of osteoporosis in the Italian population and main risk factors: results of BoneTour Campaign.BMC musculoskeletal disorders · 2016Article
- Osteoporosis Associated with Epilepsy and the Use of Anti-Epileptics-a Review.Current osteoporosis reports · 2016Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to assess the feasibility of calcaneal quantitative ultrasonography (QUS) as a screening method for increased risk of osteoporosis in a unique population of people with chronic epilepsy, intellectual disability (ID), and chronic use of antiepileptic drugs.
methodsA total of 205 patients from a long-stay care facility for people with epilepsy underwent dual-energy X-ray absorptiometry (DXA) and QUS of the calcaneus. T-scores for both DXA and QUS were calculated and correlated.
resultsA total of 195 patients (95.1%) were successfully measured with DXA and 204 (99.5%) with QUS. High correlations were found between DXA and QUS T-scores: r = 0.666 (QUS versus T-score total femur), r = 0.631 (QUS versus T-score femur neck) and r = 0.485 (QUS versus T-score lumbar spine). All correlations were statistically significant (p = 0.01).
conclusionQUS showed a strong correlation with DXA and proved to be a feasible measuring method in a population with ID and epilepsy. Including osteopenia in the screening process increases the sensitivity of QUS to identify those patients at risk for the development of bone diseases.
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