ArticleFrontiers in genetics2013
The household contact study design for genetic epidemiological studies of infectious diseases.
Article in Frontiers in genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Capturing RecentTropical medicine and infectious disease · 2024Article
- Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.PLoS genetics · 2021Article
- Phenotype Definition for "Resisters" toFrontiers in immunology · 2021Review
- Fine-mapping analysis of a chromosome 2 region linked to resistance to Mycobacterium tuberculosis infection in Uganda reveals potential regulatory variants.Genes and immunity · 2019Article
- Long-term Stability of Resistance to Latent Mycobacterium tuberculosis Infection in Highly Exposed Tuberculosis Household Contacts in Kampala, Uganda.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
- Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection.Nature reviews. Immunology · 2018Review
- Resistance and Susceptibility to Mycobacterium tuberculosis Infection and Disease in Tuberculosis Households in Kampala, Uganda.American journal of epidemiology · 2018Article
- Impact of geographic distance on appraisal delay for active TB treatment seeking in Uganda: a network analysis of the Kawempe Community Health Cohort Study.BMC public health · 2018Article
- Genomics of human pulmonary tuberculosis: from genes to pathways.Current genetic medicine reports · 2017Article
- Identification of Host Proteins Predictive of Early Stage Mycobacterium tuberculosis Infection.EBioMedicine · 2017Article
- A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa.PLoS genetics · 2017Article
- Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection.PloS one · 2017Article
- A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals.American journal of human genetics · 2016Article
- Sulfamethoxazole susceptibility of Mycobacterium tuberculosis isolates from HIV-infected Ugandan adults with tuberculosis taking trimethoprim-sulfamethoxazole prophylaxis.Antimicrobial agents and chemotherapy · 2015Article
- Polymorphisms in TICAM2 and IL1B are associated with TB.Genes and immunity · 2015Article
- Novel approaches to the analysis of family data in genetic epidemiology.Frontiers in genetics · 2015Article
- Clinical and epidemiological characteristics of individuals resistant to M. tuberculosis infection in a longitudinal TB household contact study in Kampala, Uganda.BMC infectious diseases · 2014Article
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4 authors.
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Abstract
most genetic epidemiological study designs fall into one of two categoriesfamily based and population-based (case-control). However, recent advances in statistical genetics call for study designs that combine these two approaches. We describe the household contact study design as we have applied it in our several years of study of the epidemiology of tuberculosis. Though we highlight its applicability for genetic epidemiological studies of infectious diseases, there are many facets of this design that are appealing for modern genetic studies, including the simultaneous enrollment of related and unrelated individuals, closely and distantly related individuals, collection of extensive epidemiologic and phenotypic data, and evaluation of effects of shared environment and gene by environment interaction. These study design characteristics are particularly appealing for current sequencing studies.
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