ArticleThe Journal of comparative neurology2013
Monosynaptic convergence of chorda tympani and glossopharyngeal afferents onto ascending relay neurons in the nucleus of the solitary tract: a high-resolution confocal and correlative electron microscopy approach.
Article in The Journal of comparative neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- CBLN2 promoter enables genetic access to wide-field neurons of the tree shrew superior colliculus.Cell reports methods · 2026Article
- Regulation of Rostral Nucleus of the Solitary Tract Responses to Afferent Input by A-type K+ Current.Neuroscience · 2022Article
- Cocaine- and amphetamine-regulated transcript peptide- and dopamine-containing systems interact in the ventral tegmental area of the zebra finch, Taeniopygia guttata, during dynamic changes in energy status.Brain structure & function · 2021Article
- Variable Branching Characteristics of Peripheral Taste Neurons Indicates Differential Convergence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Sweet Taste Is Complex: Signaling Cascades and Circuits Involved in Sweet Sensation.Frontiers in human neuroscience · 2021Review
- GAD65Cre Drives Reporter Expression in Multiple Taste Cell Types.Chemical senses · 2021Article
- An alternative pathway for sweet sensation: possible mechanisms and physiological relevance.Pflugers Archiv : European journal of physiology · 2020Review
- Sexual Dimorphic Distribution of Hypothalamic Tachykinin1 Cells and Their Innervations to GnRH Neurons in the Zebrafish.Frontiers in endocrinology · 2020Article
- 5-HTThe Journal of comparative neurology · 2017Article
- Immunocytochemical organization and sour taste activation in the rostral nucleus of the solitary tract of mice.The Journal of comparative neurology · 2017Article
- Inhibitory modulation of optogenetically identified neuron subtypes in the rostral solitary nucleus.Journal of neurophysiology · 2016Article
- Topographic organizations of taste-responsive neurons in the parabrachial nucleus of C57BL/6J mice: An electrophysiological mapping study.Neuroscience · 2016Article
- Neuronal connectivity between habenular glutamate-kisspeptin1 co-expressing neurons and the raphe 5-HT system.Journal of neurochemistry · 2015Article
- Feedback in the brainstem: an excitatory disynaptic pathway for control of whisking.The Journal of comparative neurology · 2015Article
- Temperature systematically modifies neural activity for sweet taste.Journal of neurophysiology · 2014Article
- Monosynaptic glutamatergic activation of locus coeruleus and other lower brainstem noradrenergic neurons by the C1 cells in mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
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2 authors.
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Abstract
Physiological studies suggest convergence of chorda tympani and glossopharyngeal afferent axons onto single neurons of the rostral nucleus of the solitary tract (rNTS), but anatomical evidence has been elusive. The current study uses high-magnification confocal microscopy to identify putative synaptic contacts from afferent fibers of the two nerves onto individual projection neurons. Imaged tissue is revisualized with electron microscopy, confirming that overlapping fluorescent signals in confocal z-stacks accurately identify appositions between labeled terminal and dendrite pairs. Monte Carlo modeling reveals that the probability of overlapping fluorophores is stochastically unrelated to the density of afferent label, suggesting that convergent innervation in the rNTS is selective rather than opportunistic. Putative synaptic contacts from each nerve are often compartmentalized onto dendrite segments of convergently innervated neurons. These results have important implications for orosensory processing in the rNTS, and the techniques presented here have applications in investigations of neural microcircuitry with an emphasis on innervation patterning.
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